Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Human IRF3 Antibody, clone 3F10    

Anti-Human IRF3 Antibody, clone 3F10

Mouse Anti-Human Monoclonal Antibody

  • WB - Anti-Human IRF3 Antibody, clone 3F10  ABD11871
    Western blot analysis of IRF3 expression on a Jurkat cell lysate using Mouse anti Human IRF3
  • IF - Anti-Human IRF3 Antibody, clone 3F10  ABD11871
    Imminoprecipitaion of IRF3 fron HeLa cells using Mouse anti Human IRF3 Lane A: Normal IgGLane B: Mouse anti Human IRF3, clone 3F10 (non-specific bands represent IgG H+L in the preparation)Immunofluorescent staining of HeLa cells with Mouse anti Human IRF3 , IRF3 , nuclei counterstained with Hoescht 3342
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14653
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 3F10
Calculated MW 47219 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Recombinant human IRF3 (amino acids 108-166) purified from E. coli.
Shelf Life 18 months from date of despatch.
Gene ID 3661
Other Names Interferon regulatory factor 3, IRF-3, IRF3
Target/Specificity Mouse anti-Human IRF3 antibody, clone 3F10 recognizes human interferon regulatory factor 3 (IRF3), a 55kDa constitutively expressed member of the IRF family, which acts as vital regulator of gene expression in innate immunity (Nociariet al.2007).IRF3 accumulates in an inactive form in the cytoplasm and then translocates to the nucleus as a homodimer, following stimuli-induced phosphorylation of specific serine/threonine residues. Association of the homodimer with p300/CBP (CREBB binding protein) forms dsRNA-activated factor 1 (DRAF1), which then activates the transcription of interferon alpha and beta and subsequent downstream interferon-induced genes (Weaveret al.1998).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human IRF3 Antibody, clone 3F10 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


1. Takahasi, K. et al. (2003) X-ray crystal structure of IRF-3 and its functional implications.
Nat. Struc. Biol. 10: 922-927.

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

Cat# ABD11871
(40 western blots)
Availability: Inquire
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions