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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human Igfbp-3 Antibody, clone 83.8F9    

Anti-Human Igfbp-3 Antibody, clone 83.8F9

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P17936
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 83.8F9
Calculated MW 31674 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A from ascites
Immunogen Recombinant human IGFBP-3.
Shelf Life 18 months from date of despatch.
Gene ID 3486
Other Names Insulin-like growth factor-binding protein 3, IBP-3, IGF-binding protein 3, IGFBP-3, IGFBP3, IBP3
Target/Specificity Mouse anti-Human IGFBP-3 clone 83.8F9 recognizes IGFBP-3, a member of the superfamily of insulin-like growth factor binding proteins that hold a central position in IGF ligand-receptor interactions through influences on both the bioavailability and distribution of IGFs in the extracellular environment. IGFBP-3 is found in human serum and has two forms of approximate molecular mass 40 and 43 kDa.IGFBP-3 binds IGF-1 and IGF-2 with similar high affinity. In the blood stream, approximately 90 % of IGFBP-3 is found in a ternary complex of 140 kDa. This complex comprises an acid-labile subunit (a-subunit), IGFBP-3 (ß-subunit) and IGF-1 or IGF-2. This binding prolongs the metabolic half-life of IGF-1 in circulation and serves as a metabolic reservoir of IGF-1.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Igfbp-3 Antibody, clone 83.8F9 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11876
(40 western blots)
Availability: Inquire
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