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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human Cathepsin B Antibody (HRP)   

Anti-Human Cathepsin B Antibody (FITC)

Sheep Anti-Human Polyclonal Antibody

  • E - Anti-Human Cathepsin B Antibody (FITC) ABD11888
    Cathepsin B detected with Sheep anti Cathepsin B:HRP
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P07858
Reactivity Human
Host Sheep
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 37822 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Native, from placenta
Shelf Life 18 months from the date of despatch.
Gene ID 1508
Other Names Cathepsin B,, APP secretase, APPS, Cathepsin B1, Cathepsin B light chain, Cathepsin B heavy chain, CTSB, CPSB
Target/Specificity Sheep anti-Human cathepsin B antibody detects cathepsin B, a lysosomal cysteine protease which functions as both a endopeptidase and a carboxypeptidase. Together with cathepsins D and L, cathepsin B is one of the most abundant proteases in the lysosome, and participates in intracellular protein degradation.Cathepsin B is thought to play an increasingly important role in apoptosis and its release from the lysosome under cell stress leads to Bid cleavage, cytochrome C release and nuclear fragmentation.Cathepsin B is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete processing of APP is thought to be a causative factor in Alzheimer disease.Over-expression of cathepsin B has been associated with oesophageal adenocarcinoma and other tumours, and has in particular been implicated in tumour invasion and metastasis.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin
Storage Store at +4℃ or -20℃.
PrecautionsAnti-Human Cathepsin B Antibody (FITC) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11888
(40 western blots)
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Bulk Size
Seasonal Special on Bulk Order
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