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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human Ceruloplasmin Antibody (HRP)   

Anti-Human Ceruloplasmin Antibody

Sheep Anti-Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P00450
Reactivity Human
Host Sheep
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 122205 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Highly pure human ceruloplasmin
Shelf Life 18 months from the date of despatch.
Gene ID 1356
Other Names Ceruloplasmin,, Ferroxidase, CP
Target/Specificity Sheep anti-Human ceruloplasmin antibody detects ceruloplasmin, a ~132kDa metalloprotein that is secreted into the plasma by liver hepatocytes and activated monocytes/macrophages. Ceruloplasmin functions in copper transport, iron homeostasis, antioxidant defence, angiogenesis and coagulation.Deficiency in ceruloplasmin is termed aceruloplasminemia, an autosomal recessive disorder which leads to iron accumulation and tissue damage, in particular in the brain and visceral organs. Clinical features include retinal degeneration, diabetes mellitus and neurological disturbances.Elevated plasma ceruloplasmin has been shown to pose an increased risk in atherosclerosis and myocardial infarction.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Ceruloplasmin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Balmaña M (2015) Identification of potential pancreatic cancer serum markers: Increased sialyl-Lewis X on ceruloplasmin.
Clin Chim Acta. pii: S0009-8981(15)00021-2. 1. Mazumder, B. et al. (2005) Regulation of macrophage ceruloplasmin gene expression: one paradigm of 3'-UTR-mediated translational control.
Mol. Cells. 20: 167-172.

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Cat# ABD11889
(40 western blots)
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