|Calculated MW||22659 Da|
|Purification||Antisera to bovine glutathione peroxidase were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Glutathione peroxidase from bovine erythrocytes.|
|Shelf Life||18 months from the date of despatch.|
|Other Names||Glutathione peroxidase 1, GPx-1, GSHPx-1, 220.127.116.11, Cellular glutathione peroxidase, GPX1|
|Target/Specificity||Sheep anti-Bovine glutathione peroxidase antibody detects human glutathione peroxidise (GSH-Px), a selenium-containing tetrameric enzyme found in mammalian erythrocytes. GSH-Px has an important role in protecting cellular and subcellular membranes from oxidative damage, and functions to detoxify peroxide though the reduction of hydrogen peroxide and organic peroxides.An increase in GSH-Px in tumour cells may be associated with resistance to drugs that act by generating reactive oxygen species, for example doxorubicin.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Bovine Glutathione Peroxidase Antibody (Alk. Phos.) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Kankofer, M. et al. (2013) The presence of SOD 1 and GSH-Px in bovine retained and properly released foetal membranes.Reprod Domest Anim. 48 (4): 699-704.1. MILLS, G.C. (1957) Hemoglobin catabolism. I. Glutathione peroxidase, an erythrocyte enzyme which protects hemoglobin from oxidative breakdown.J Biol Chem. 229 (1): 189-97.
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