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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human Haptoglobin Antibody (HRP)   

Anti-Human Haptoglobin Antibody

Sheep Anti-Human Polyclonal Antibody

  • E - Anti-Human Haptoglobin Antibody  ABD11896
    Human Haptoglobin detected with Sheep anti Human Haptoglobin: HRP
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P00738
Reactivity Human
Host Sheep
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 45205 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Native, purified human haptoglobin from serum.
Shelf Life 18 months from the date of despatch.
Gene ID 3240
Other Names Haptoglobin, Zonulin, Haptoglobin alpha chain, Haptoglobin beta chain, HP
Target/Specificity Sheep anti-Human Haptoglobin antibody detects haptoglobin, also known as Hp, an acute phase plasma glycoprotein synthesized by the liver in response to infection or inflammation. Haptoglobin binds haemoglobin released by erythrocytes with high affinity, and functions to block the oxidative activity of haemoglobin and prevent renal damage. The haptoglobin-haemoglobin complex is rapidly removed from the circulation by monocytes and macrophages, via the receptor CD163.The haptoglobin genotype has been demonstrated to be an independent risk factor for cardiovascular disease in multiple epidemiological studies.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Haptoglobin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Carter, K. and Worwood, M. (2007) Haptoglobin: a review of the major allele frequencies worldwide and their association with diseases.
Int. J. Lab. Hematol. 29: 92-110. 2. Guetta, J. et al. (2007) Haptoglobin genotype modulates the balance of Th1/Th2 cytokines produced by macrophages exposed to free hemoglobin.
Atherosclerosis. 191: 48-53. 3. Araki, H. et al. (2015) Haptoglobin promoter polymorphism rs5472 as a prognostic biomarker for peptide vaccine efficacy in castration-resistant prostate cancer patients.
Cancer Immunol Immunother. Oct 1. [Epub ahead of print] 4. Soejima, M. et al. (2014) Genetic factors associated with serum haptoglobin level in a Japanese population.
Clin Chim Acta. 433: 54-7.

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Cat# ABD11896
(40 western blots)
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