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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Mouse Interleukin-4 Antibody (Biotin)   

Anti-Mouse Interleukin-4 Antibody

Rabbit Anti-Mouse Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E, Func
Primary Accession P07750
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 15834 Da
Additional Information
Purification Antisera to mouse IL-4 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen Recombinant mouse IL-4
Shelf Life 12 months from date of reconstitution.
Gene ID 16189
Other Names Interleukin-4, IL-4, B-cell IgG differentiation factor, B-cell growth factor 1, B-cell stimulatory factor 1, BSF-1, IGG1 induction factor, Lymphocyte stimulatory factor 1, Il4, Il-4
Target/Specificity Rabbit anti-Mouse Interleukin-4 antibody recognizes mouse interleukin-4 (IL-4), also known as B-cell stimulatory factor 1, a 120 amino acid pleiotropic cytokine cleaved from a 140 amino acid precursor which interacts with multiple cell lineages, including T cells, fibroblasts and macrophages (Crawfordet al.1987).Interleukin-4 is one of the most important factors involved in B cell IgG1 and IgE class switching (Winteret al.1987). IL-4 acts as a regulator of low affinity Fc receptor for IgE (CD23) expression on both lymphocytes and monocytes (Miyajimaet al.1991,Hudaket al.1987). IL-4 acts through binding to it's cognate receptor CD124, a receptor which also binds the related cytokine IL-13.Interleukin -4 plays an important role in the alternative activation of murine macrophages as indicated by the ability to potently up-regulate the expression and activity of CD206, the macrophage mannose receptor (Steinet al.1992).
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Mouse Interleukin-4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. de Barros, V.E.D. et al. (2011) An Experimental Model of Meningoencephalomyelitis by Rocio Flavivirus in Balb/C Mice: Inflammatory Response, Cytokine Production, and Histopathology
Am J Trop Med Hyg. 85: 363-73. 2. Kim, S.R. et al. (2013) Endoplasmic reticulum stress influences bronchial asthma pathogenesis by modulating nuclear factor ?B activation.
J Allergy Clin Immunol. pii: S0091-6749(13)01382-1.

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Cat# ABD11916
(40 western blots)
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