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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Rat TNF alpha Antibody (Biotin)   

Anti-Rat TNF alpha Antibody

Rabbit Anti-Rat Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, Func
Primary Accession P16599
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 25806 Da
Additional Information
Purification Antisera to rat TNF alpha were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen Recombinant rat TNF alpha (PRP16).
Shelf Life 12 months from date of reconstitution.
Gene ID 103694380;24835
Other Names Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Tumor necrosis factor, membrane form, N-terminal fragment, NTF, Intracellular domain 1, ICD1, Intracellular domain 2, ICD2, C-domain 1, C-domain 2, Tumor necrosis factor, soluble form, Tnf, Tnfa, Tnfsf2
Target/Specificity Rabbit anti-Rat TNF alpha antibody recognizes rat tumor necrosis factor alpha (TNFα), also known as Cachectin or Tumor necrosis factor ligand superfamily member 2. Rat TNFα is a 235 amino acid ~17 kDa single pass type II O-linked transmembrane glycoprotein, it also exists as a secreted cytokine through cleavage between residues 79 and 80. TNFα is produced by many cell types including macrophages, monocytes, neutrophils and a population of activated NK cells.
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Rat TNF alpha Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Halin, S. et al. (2010) Pigment epithelium-derived factor stimulates tumor macrophage recruitment and isdownregulated by the prostate tumor microenvironment.
Neoplasia. 12: 336-45. 2. Khandelwal, P.J. et al. (2010) Parkinson-related parkin reduces a-Synuclein phosphorylation in a gene transfer model.
Mol Neurodegener. 5: 47. 3. Sandoval, J. et al. (2010) Ordered transcriptional factor recruitment and epigenetic regulation of tnf-alpha in necrotizing acute pancreatitis.
Cell Mol Life Sci. 67: 1687-97. 4. Irwin, M.W. et al. (1999) Tissue expression and immunolocalization of tumor necrosis factor-alpha in postinfarction dysfunctional myocardium.
Circulation. 99: 1492-8. 5. El-Kharashi, O.A. et al. (2011) The Potential Pharmacological and Histological Benefits of Carvedilol on the Hippocampal Post- Stroke Seizures in Rats
Life Science Journal, 8: 951-60 6. Elgarf, A.S. et al. (2014) Lipopolysaccharide repeated challenge followed by chronic mild stress protocol introduces a combined model of depression in rats: reversibility by imipramine and pentoxifylline.
Pharmacol Biochem Behav. 126: 152-62. 7. Aharon-Hananel G et al. (2015) Antidiabetic Effect of Interleukin-1β Antibody Therapy Through β-Cell Protection in the Cohen Diabetes-Sensitive Rat.
Diabetes. 64 (5): 1780-5.

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Cat# ABD11934
(40 western blots)
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