|Application ||WB, FC, E, Func|
|Calculated MW||15238 Da|
|Purification||Antisera to human IL-5 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Recombinant human IL-5.|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Interleukin-5, IL-5, B-cell differentiation factor I, Eosinophil differentiation factor, T-cell replacing factor, TRF, IL5|
|Target/Specificity||Rabbit anti-Human Interleukin-5 antibody recognizes human IL-5 (Interleukin-5), a disulphide-linked homodimer consisting of two 115 amino acid chains, which is homologous to mouse eosinophil differentiation factor (EDF) and is produced by mast cells, eosinophils and T cells.IL-5 is a lineage-specific cytokine involved in the development and stimulation of eosinophils, and has been linked with diseases involving abnormally high levels of eosinophils, including parasitic infections and allergic airways eosinophilia, the major pathological symptom of allergic asthma.|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Human Interleukin-5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Campbell, H.D. et al. (1987) Molecular cloning, nucleotide sequence, and expression of the gene encoding human Eosinophil Differentiation Factor (Interleukin 5). P.N.A.S. 84: 6629-6633.2. Wang, J. et al. (1998) Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia. J. Clin. Invest. 102: 1132-1141.
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