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Anti-Human Interleukin-6 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IF - Anti-Human Interleukin-6 Antibody  ABD11946
    Immunofluorescent staining of BJ human foreskin fibroblast cells with Rabbit anti Human interleukin-6 , green; counterstained with tubulin, red and nuclei, blue
  • IHC-P - Anti-Human Interleukin-6 Antibody  ABD11946
    Staining of formalin fixed, paraffin embedded human cervical squamous cell carcinoma with Rabbit anti Human interleukin-6
  • IF - Anti-Human Interleukin-6 Antibody  ABD11946
    Immunofluorescent staining of HeLa cells with Rabbit anti Human interleukin-6 , green; counterstained with tubulin, red and nuclei, blue
  • IF - Anti-Human Interleukin-6 Antibody  ABD11946
    Immunofluorescent staining of PC3, prostate cancer cells with Rabbit anti Human interleukin-6 , green; counterstained with tubulin, red and nuclei, blue
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E, Func
Primary Accession P05231
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 23718 Da
Additional Information
Purification Antisera to human IL-6 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Recombinant human IL-6(PHP045)
Shelf Life 12 months from date of reconstitution.
Gene ID 3569
Other Names Interleukin-6, IL-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2, IL6, IFNB2
Target/Specificity Rabbit anti-Human Interleukin-6 antibody is specific for human IL-6 (Interleukin-6), a 184 amino acid multifunctional pro-inflammatory cytokine, secreted by activated T cells, macrophages, endothelial cells, fibroblasts and osteoblasts. The diverse biological properties of IL-6 include the principle inducer of the acute phase response in the liver, stimulation of B cell differentiation and subsequent immunoglobulin production, promotion of hybridoma growth, regulation of bone metabolism and stimulation of energy mobilisation in muscle and fatty tissue. IL-6 signals through a membrane bound receptor complex consisting of the ligand-binding IL-6Ra chain (CD126) and the signal-transducing component gp130 (CD130), but can also stimulate cells expressing gp130 through a soluble IL-6R. Rabbit anti-Human Interleukin-6 antibody has been shown to inhibit the biological activity of Human IL-6.
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Human Interleukin-6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Yasukawa, K. et al. (1987) Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene.
EMBO. J. 6: 2939-2945.2. Peters, M. et al. (1998) Interleukin-6 and soluble interleukin-6 receptor: direct stimulation of gp130 and hematopoiesis.
BLOOD. 92: 3495-3504.

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Cat# ABD11946
(40 western blots)
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