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Anti-Human Leptin Antibody

Rabbit Anti-Human Polyclonal Antibody

     
  • IHC - Anti-Human Leptin Antibody  ABD11956
    Formalin fixed, paraffin embedded human breast invasive ductal carcimoma stained with Rabbit anti Human leptin following heat mediated antigen retrieval using sodium citrate buffer (pH6.0)
  • IHC-P - Anti-Human Leptin Antibody  ABD11956
    Formalin fixed, paraffin embedded human breast invasive ductal carcimoma stained with Rabbit anti Human leptin following heat mediated antigen retrieval using sodium citrate buffer (pH6.0)
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P41159
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 18641 Da
Additional Information
Purification Antiserum to human leptin was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen Recombinant human leptin(PHP198)
Shelf Life 12 months from date of reconstitution.
Gene ID 3952
Other Names Leptin, Obese protein, Obesity factor, LEP, OB, OBS
Target/Specificity This product recognises human leptin, a 16KDa major adipose-derived hormone and member of the leptin family, which plays a key role in appetite control and the regulation of energy expenditure.Secreted leptin associates with proteins within the bloodstream and is transported to the brain, where it inhibits or up-regulates the activity of neuropeptides such as neuropeptide Y (NPY) and alpha-melanocyte-stimulating hormone respectively. Leptin is a recognised marker of obesity, with a correlation between circulating levels of leptin and body fat mass, and defects in leptin production result in severe obesity. Regulators of leptin expression include insulin, cortisol, cAMP and thiazolidinediones.
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Human Leptin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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References

1. Paracchini, V. et al. (2005) Genetics of leptin and obesity: a HuGE review.
Am. J. Epidemiol. 162: 101-114.

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Cat# ABD11956
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