|Application ||WB, E|
|Calculated MW||7697 Da|
|Purification||Antiserum to human defensin beta 3 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Recombinant human defensinβ-3|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Beta-defensin 103, Beta-defensin 3, BD-3, DEFB-3, HBD3, hBD-3, Defensin, beta 103, Defensin-like protein, DEFB103A, BD3, DEFB103, DEFB3|
|Target/Specificity||Rabbit anti-human Defensinβ-3 polyclonal antibody specifically recognizes human defensin beta 3 (BD-3), a 45aa ~5kDa cationic non-haemolytic antimicrobial peptide expressed by epithelial cells and member of the beta-defensin family. Defensin beta 3 is highly expressed in the skin and tonsils and at lower levels in other tissues(Harderet al.2001).Defensin beta 3 plays an important role in the innate immune response to potentially pathogenic microbes, including multiresistantS. aureus and vancomycin-resistant E. faecium.|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Human Defensin beta 3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Boesch, A.W. et al. (2013) A Multiplexed Assay to Detect Antimicrobial Peptides in Biological Fluids and Cell Secretions.J Immunol Methods. pii: S0022-1759(13)00241-X.1. Harder, J. et al. (2001) Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic.J Biol Chem. 276: 5707-13.
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