|Application ||WB, E|
|Calculated MW||27818 Da|
|Purification||Antiserum to human BDNF were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Recombinant human BDNF|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Brain-derived neurotrophic factor, BDNF, Abrineurin, BDNF|
|Target/Specificity||Rabbit anti-Human BDNF antibody recognizes human BDNF (brain-derived neurotrophic factor), a potent neurotrophin and member of the NGF-beta family, secreted from dense core vesicles, which promotes the growth, differentiation and survival of neurons within, or directly connected to, the central nervous system (CNS).BDNF signals through binding to the high affinity receptor trkB, and also binds to the low affinity neurotrophin receptor LNGFR. Studies have shown the involvement of BDNF in the modulation of short-term synaptic function and in the formation of long-term memory, and reduced levels of BDNF are seen in patients with Alzheimer's and Huntington disease.|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Human BDNF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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