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Anti-Human TIMP-1 Antibody

Rabbit Anti-Human Polyclonal Antibody

     
  • IHC - Anti-Human TIMP-1 Antibody  ABD11965
    Formalin fixed, paraffin embedded human breast invasive ductal carcinoma stained with Rabbit anti Human TIMP-1 following enzyme mediated antigen retrieval using proteinase K
  • IHC-P - Anti-Human TIMP-1 Antibody  ABD11965
    Formalin fixed, paraffin embedded human breast invasive ductal carcinoma stained with Rabbit anti Human TIMP-1 following enzyme mediated antigen retrieval using proteinase K
  • IHC-P - Anti-Human TIMP-1 Antibody  ABD11965
    Formalin fixed, paraffin embedded human breast invasive ductal carcinoma stained with Rabbit anti Human TIMP-1 following enzyme mediated antigen retrieval using proteinase K
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, Func
Primary Accession P01033
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 23171 Da
Additional Information
Purification Antiserum to human TIMP-1 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen Recombinant human TIMP-1
Shelf Life 12 months from date of reconstitution.
Gene ID 7076
Other Names Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP
Target/Specificity Rabbit anti-Human TIMP-1 antibody specifically recognizes human TIMP-1 (Tissue Inhibitor of Metalloproteinase -1), a secreted glycoprotein and member of the protease inhibitor I35 (TIMP) family, which is expressed by a wide range of cells, including microvascular endothelial cells, smooth muscle cells, mesangial cells, and some fibroblasts. TIMP-1 acts as a natural extracellular inhibitor of MMPs (matrix metalloproteinases), a group of peptidases involved in degradation of the extracellular matrix, and is also involved in erythropoiesis, through the simulation of the proliferation/differentiation of erythroid progenitors. Studies have shown that a correlation between localized concentrations of TIMP-1 and TIMP-3, may determine cell fate, and that increased expression of TIMP-1, may act as an inhibitor/suppressor of invasive cell growth.
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Human TIMP-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD11965
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