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Anti-Human Interleukin-1 alpha Antibody (Biotin)

Rabbit Anti-Human Polyclonal Antibody

     
  • IHC - Anti-Human Interleukin-1 alpha Antibody (Biotin) ABD11967
    Formalin fixed, paraffin embedded normal human skin stained with Rabbit anti Human IL-1β following enzume mediated antigen retrieval using proteinase K
  • IHC-P - Anti-Human Interleukin-1 alpha Antibody (Biotin) ABD11967
    Formalin fixed, paraffin embedded normal human skin stained with Rabbit anti Human IL-1β following enzume mediated antigen retrieval using proteinase K
  • IHC-P - Anti-Human Interleukin-1 alpha Antibody (Biotin) ABD11967
    Formalin fixed, paraffin embedded normal human skin stained with Rabbit anti Human IL-1β following enzume mediated antigen retrieval using proteinase K
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P01583
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 30607 Da
Additional Information
Purification Antisera to human IL-1 alpha were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Recombinant human IL-1 alpha. (PHP040)
Shelf Life 12 months from date of reconstitution.
Gene ID 3552
Other Names Interleukin-1 alpha, IL-1 alpha, Hematopoietin-1, IL1A, IL1F1
Target/Specificity Rabbit anti-Human Interleukin-1 alpha antibody recognizes human IL-1 alpha (Interleukin-1 alpha), an 18kDa multi-functional pro-inflammatory cytokine which belongs to the IL-1 family of proteins, and is produced by a variety of cells including activated macrophages, monocytes and keratinocytes.IL-1 alpha and IL-1 beta have been identified as two distinct IL-1 proteins which bind to the same type 1 Interleukin 1 receptor (IL1R1). Biological properties of IL-1 alpha include stimulation of thymocyte proliferation by induction of IL-2 release, B-cell proliferation and maturation, and fibroblast growth factor activity.
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Human Interleukin-1 alpha Antibody (Biotin) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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References

1. Gubler, U. et al. (1986) Recombinant human Interleukin-1α: purification and biological characterization.
J. Immunol. 136: 2492-2497. 2. Kilian, P.L. et al. (1986) Interleukin 1α and Interleukin 1b bind to the same receptor on T cells.
J. Immunol. 136: 4509-4514.

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Cat# ABD11967
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