|Application ||IHC-P, IHC-F|
|Immunogen||Bovine brain S-100.|
|Target/Specificity||Rabbit anti-S100 Protein antibody reacts with human S-100 A and S-100 B. This protein is present in brain glial cells and in ependymal cells. ABD11972H also stains Schwann cells of the peripheral nervous system.Among tumours of the human central and peripheral nervous systems, schwannomas, ependymomas and astrogliomas of different stages, including glioblastomas show positive reactions. S100 can be detected in almost all benign naevi and malignant melanocytic tumours of the skin and in Langerhans cells in the skin.|
|Precautions||Anti-S100 Protein Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Moore, B.W. (1965) A soluble protein characteristic of the nervous system.Biochem. Biophys. Res. Comm; 19: 739-744. 2. Kindblom, L.G. et al. (1984) S-100 protein in melanocytic tumors. An immunohistochemical investigation of benign and malignant melanocytic tumors and metastases of malignant melanoma and a characterization of the antigen in comparison to human brain.Acta. Path. Micro. Immunol Scand. 92: 219-230. 3. Lauriola, L. et al. (1984) Detection of S-100 labelled cells in nasopharyngeal carcinoma. J. Clin. Path. 37: 1235-1238. 4. Lam, T.T. et al. (2003) Early glial responses after acute elevated intraocular pressure in rats.Invest Ophthalmol Vis Sci. 44:638-645.
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