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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Human Interleukin-17 Antibody    

Anti-Human Interleukin-17 Antibody (Biotin)

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human Interleukin-17 Antibody (Biotin) ABD11973
    Formalin fixed, paraffin embedded human breast invasive ductal carcinoma stained with Goat anti Human IL-17A following heat mediated antigen retrieval with sodium citrate buffer (pH6.0)
  • IHC-P - Anti-Human Interleukin-17 Antibody (Biotin) ABD11973
    Staining of formalin fixed,paraffin embedded human breast invasive ductal carcinoma with Rabbit anti Human interleukin-17
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16552
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 17504 Da
Additional Information
Purification Antisera to human IL-17 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by antigen affinity chromatography
Immunogen Recombinant human IL-17
Shelf Life 12 months from date of reconstitution.
Gene ID 3605
Other Names Interleukin-17A, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, IL17A, CTLA8, IL17
Target/Specificity Rabbit anti-Human Interleukin-17 antibody recognizes human IL-17 (Interleukin-17/17A), a 32kDa disulfide-linked homodimer consisting of two 136 amino acid chains, which belongs to the IL-17 family (classified as IL-17A to IL-17F), and signals through the IL-17 receptor (IL-17R/CDw217).IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Human Interleukin-17 Antibody (Biotin) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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2. Parsonage, G. et al. (2008) Prolonged, granulocyte-macrophage colony-stimulating factor-dependent, neutrophilsurvival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha.
Arthritis Res Ther. 10: R47.1. Gaffen, S.L. (2004) Biology of recently discovered cytokines; Interleukin-17 – a unique inflammatory cytokine with roles in bone biology and arthritis.
Arth. Res. and Therapy. 6: 240-247.

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Cat# ABD11973
(40 western blots)
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