|Application ||IHC-P, IHC-F|
|Calculated MW||43653 Da|
|Purification||Antisera to human p53 were raised by repeated immunisation of rabbits with highly purified antigen.|
|Immunogen||Recombinant human p53|
|Shelf Life||18 months from date of despatch.|
|Other Names||Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53, TP53, P53|
|Target/Specificity||Rabbit anti-Human p53 antibody recognizes both the wild type and mutant forms of p53. The oncoprotein p53 is an intensively studied tumour suppressor protein, which has a vital role in the control of cell growth.In normal circumstances cells arrest during the G1/G2 phase of the cell cycle, and undertake any DNA repair processes that are necessary. This arrest is mediated by p53, and if p53 is absent or damaged cells with cancerous potential may be able to continue through the cell cycle.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3); 1% Bovine Serum Albumin;|
|Storage||Store at +4℃. DO NOT FREEZE.|
|Precautions||Anti-Human p53 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Yan, G. et al. (2004) Rapid and sensitive immunomagnetic-electrochemiluminescent detection of p53 antibodies in human serum.J Immunol Methods. 288: 47-54.
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