|Application ||WB, IHC-P, E, Func|
|Calculated MW||19348 Da|
|Purification||Antisera to human IFNγ were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Recombinant human IFNγ|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Interferon gamma, IFN-gamma, Immune interferon, IFNG|
|Target/Specificity||Rabbit anti-Human Interferon gamma antibody recognizes human IFN-gamma (Interferon-gamma), a 143 amino acid regulatory cytokine and member of the Type II interferon family. IFN-gamma is involved in the regulation of the immune and inflammatory responses and is secreted primarily by mitogen and antigen activated T lymphocytes and natural killer cells (NK).IFN-gamma is a multifunctional cytokine which signals through the IFN-gamma receptor (IFNGR), found on most immune cells. Properties of IFN-gamma include recruitment of leucocytes to sites of infection, inducement of MHC class I and II antigens, stimulation of anti-microbial and anti-tumour responses of macrophages, Nk cells and neutrophils, and has also been shown to potentiate the antiproliferative effects of IFN-alpha and IFN-beta.|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Human Interferon gamma Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Rinderknecht, E. et al. (1984) Natural human Interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation* .J. Biol. Chem. 259: 6790-6797.2. Goldberg, M. et al. (1989) Regulation of macrophage growth and antiviral activity by Interferon-gamma. J. Cell Biol. 109: 1331-1340.
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