|Calculated MW||27683 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Shelf Life||18 months from date of despatch.|
|Other Names||CD48 antigen, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, SLAM family member 2, SLAMF2, Signaling lymphocytic activation molecule 2, TCT.1, CD48, CD48, BCM1, BLAST1|
|Target/Specificity||Mouse anti-Human CD48 antibody, clone MEM-102 recognizes to the 45kDa leucocyte surface glycoprotein specific for the CD48 antigen which is closely related to the activation antigen, Blast-1.Mouse anti-Human CD48 antibody, clone MEM-102 is useful in the detection of CD48 positive cells and may be used in studies to differentiate haemapoietic tumors, sarcomas and melanomas.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin|
|Storage||Prior to reconstitution store at +4℃.|
|Precautions||Anti-Human CD48 Antibody, clone MEM-102 (APC) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Horejsi, V. et al. (1988) Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74).Fol. Biol. (Praha). 34: 23-34. 2. Korinek, V. et al. (1991) The human leucocyte antigen CD48 (MEM-102) is closely related to the activation marker Blast-1. Immunogenetics. 33: 108-112. 3. Cinek, T. and Horejsi, V. (1992) The nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-anchored membrane glycoproteins and protein tyrosine kinases. J. Immunol. 149: 2262-2270. 4. Staffler, G. et al. (2003) Selective inhibition of T cell activation via CD147 through novel modulation of lipid rafts. J. Immunol. 171: 1707-1714. 5. Larochelle, A. et al. (2011) Human and rhesus macaque hematopoietic stem cells cannot be purified based only on SLAM family markers.Blood. 117:1550-4. 6. Enose-Akahata, Y. et al. (2009) High expression of CD244 and SAP regulated CD8 T cell responses of patients with HTLV-I associated neurologic disease.PLoS Pathog. 5: e1000682. 7. Fukushima, K. et al. (2005) Functional role played by the glycosylphosphatidylinositol anchor glycan of CD48 in interleukin-18-induced interferon-gamma production.J Biol Chem. 280: 18056-62. 8. Kanuga, N. et al. (2002) Characterization of genetically modified human retinal pigment epithelial cells developed for in vitro and transplantation studies.Invest Ophthalmol Vis Sci. 43: 546-55.
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