Anti-Horse MHC Class II Monomorphic Antibody, clone CVS20 (FITC)
Mouse Anti-Horse Monoclonal Antibody
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Shelf Life||12 months from date of reconstitution.|
|Target/Specificity||Mouse anti-Horse MHC Class II Monomorphic antibody, clone CVS20 recognizes monomorphic equine MHC Class II and was classified at the International Equine Leucocyte Antigen Workshop. Clone CVS20 reacts with all equine B cells and 95% of equine T cells.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In horses, this is referred to as the equine leukocyte antigen (ELA) region.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or -20℃.|
|Precautions||Anti-Horse MHC Class II Monomorphic Antibody, clone CVS20 (FITC) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Kydd, J.H. & Antczak. D.F. (1991) Report of the First International Workshop on Equine Leucocyte Antigens, Cambridge, UK, July 1991Equine Immunol. 4: 5. 2. Lunn, D.P. et al. (1998) Report of the Second Equine Leucocyte Antigen Workshop, Squaw valley, California, July 1995. Vet. Immunol. Immunopathol. 62: 101-143. 3. Weiss, D. et al. (2001) Regulation of expression of major histocompatibility antigens by bovine macrophages infected with Mycobacterium avium subsp. paratuberculosis or Mycobacterium avium subsp. avium.Infect. Immun. 69 (2): 1002 - 1008. 4. Out, T. et al. (2002) Local T-cell activation after segmental allergen challenge in the lungs of allergic dogs. Immunology. 105: 499 - 508. 5. Carrade, D.D. et al. (2011) Clinicopathologic findings following intra-articular injection of autologous and allogeneic placentally derived equine mesenchymal stem cells in horses.Cytotherapy. 13: 419-30. 6. Catchpole, B. et al. (2002) Generation of blood-derived dendritic cells in dogs with oral malignant melanoma.J Comp Pathol. 126: 238-41. 7. Weiss, D.J. et al. (2006) Mucosal immune response in cattle with subclinical Johne's disease.Vet Pathol. 43: 127-35. 8. Weiss, D.J. (2001) Evaluation of proliferative disorders in canine bone marrow by use of flow cytometric scatter plots and monoclonal antibodies.Vet Pathol. 38: 512-8. 9. Sassa, Y. et al. (2010) Bovine macrophage degradation of scrapie and BSE PrPScVet Immunol Immunopathol. 133: 33-9. 10. Carrade, D.D. et al. (2012) Comparative Analysis of the Immunomodulatory Properties of Equine Adult-Derived Mesenchymal Stem Cells.Cell Medicine. 4: 1-11. 11. Bertone Alicia (2016) Cathepsin K inhibition renders equine bone marrow nucleated cells hypo-responsive to LPS and unmethylated CpG stimulation in vitroComparative Immunology, Microbiology and Infectious Diseases. Feb 27 [Epub ahead of print].1. Burk, J. et al. (2013) Equine cellular therapy-from stall to bench to bedside?Cytometry A. 83: 103-13
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