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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Mouse CD4 Antibody, clone YTS177.9 (RPE)   

Anti-Mouse CD4 Antibody, clone YTS177.9

Rat Anti-Mouse Monoclonal Antibody

  • FC - Anti-Mouse CD4 Antibody, clone YTS177.9  ABD12024
    Staining of mouse peripheral blood lymphocytes with Rat anti Mouse CD4:FITC
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, Func
Primary Accession P06332
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names YTS177.9
Calculated MW 51297 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatent.
Immunogen Mouse spleen cells
Shelf Life 18 months from date of despatch.
Gene ID 12504
Other Names T-cell surface glycoprotein CD4, T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, CD4, Cd4
Target/Specificity Rat anti-Mouse CD4 antibody, clone YTS177.9 reacts with the Mouse CD4 antigen, non polymorphic epitope (Qinet al.1990). Rat anti-Mouse CD4 antibody, Rat anti-Mouse CD4 antibody, clone YTS177.9 reacts with CD4 transfectants (Cobboldet al.1990).Rat anti-Mouse CD4 antibody, clone YTS177.9 also blocks MHC-II dependant T-cell responses in vitroandin vivo and induces tolerance (Qinet al.1990) and Cobboldet al.1990).
Preservative & Stabilisers Preservative Free
Storage Store at -20℃ only.
PrecautionsAnti-Mouse CD4 Antibody, clone YTS177.9 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Qin, S.X. et al. (1990) Induction of tolerance in peripheral T cells with monoclonal antibodies.
Eur J Immunol. 20 (12): 2737-45. 2. Cobbold, S.P. et al. (1990) The induction of skin graft tolerance in major histocompatibility complex-mismatched or primed recipients: primed T cells can be tolerized in the periphery with anti-CD4 and anti-CD8 antibodies.
Eur J Immunol. 20 (12): 2747-55. 3. Wise, M.P. et al. (1998) Linked suppression of skin graft rejection can operate through indirect recognition.
J Immunol. 161 (11): 5813-6. 4. Carlring, J. et al. (2012) Conjugation of lymphoma idiotype to CD40 antibody enhances lymphoma vaccine immunogenicity and antitumor effects in mice.
Blood. 119 (9): 2056-65. 5. Agua-Doce, A. and Graca, L. (2011) Prevention of house dust mite induced allergic airways disease in mice through immune tolerance.
PLoS One. 6: e22320. 6. Daley, S.R. et al. (2007) A key role for TGF-beta signaling to T cells in the long-term acceptance of allografts.
J Immunol. 179: 3648-54. 7. Saunders, A. et al. (2009) Expression of GIMAP1, a GTPase of the immunity-associated protein family, is not up-regulated in malaria.
Malar J. 8: 53. 8. Carlring, J. et al. (2012) Conjugation of lymphoma idiotype to CD40 antibody enhances lymphoma vaccine immunogenicity and antitumor effects in mice.
Blood. 119: 2056-65.

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Cat# ABD12024
(40 western blots)
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