|Application ||FC, Func|
|Calculated MW||51297 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatent.|
|Immunogen||Mouse spleen cells|
|Shelf Life||18 months from date of despatch.|
|Other Names||T-cell surface glycoprotein CD4, T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, CD4, Cd4|
|Target/Specificity||Rat anti-Mouse CD4 antibody, clone YTS177.9 reacts with the Mouse CD4 antigen, non polymorphic epitope (Qinet al.1990). Rat anti-Mouse CD4 antibody, Rat anti-Mouse CD4 antibody, clone YTS177.9 reacts with CD4 transfectants (Cobboldet al.1990).Rat anti-Mouse CD4 antibody, clone YTS177.9 also blocks MHC-II dependant T-cell responses in vitroandin vivo and induces tolerance (Qinet al.1990) and Cobboldet al.1990).|
|Preservative & Stabilisers||Preservative Free|
|Storage||Store at -20℃ only.|
|Precautions||Anti-Mouse CD4 Antibody, clone YTS177.9 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Qin, S.X. et al. (1990) Induction of tolerance in peripheral T cells with monoclonal antibodies.Eur J Immunol. 20 (12): 2737-45. 2. Cobbold, S.P. et al. (1990) The induction of skin graft tolerance in major histocompatibility complex-mismatched or primed recipients: primed T cells can be tolerized in the periphery with anti-CD4 and anti-CD8 antibodies.Eur J Immunol. 20 (12): 2747-55. 3. Wise, M.P. et al. (1998) Linked suppression of skin graft rejection can operate through indirect recognition.J Immunol. 161 (11): 5813-6. 4. Carlring, J. et al. (2012) Conjugation of lymphoma idiotype to CD40 antibody enhances lymphoma vaccine immunogenicity and antitumor effects in mice.Blood. 119 (9): 2056-65. 5. Agua-Doce, A. and Graca, L. (2011) Prevention of house dust mite induced allergic airways disease in mice through immune tolerance.PLoS One. 6: e22320. 6. Daley, S.R. et al. (2007) A key role for TGF-beta signaling to T cells in the long-term acceptance of allografts.J Immunol. 179: 3648-54. 7. Saunders, A. et al. (2009) Expression of GIMAP1, a GTPase of the immunity-associated protein family, is not up-regulated in malaria.Malar J. 8: 53. 8. Carlring, J. et al. (2012) Conjugation of lymphoma idiotype to CD40 antibody enhances lymphoma vaccine immunogenicity and antitumor effects in mice.Blood. 119: 2056-65.
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