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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Human CD49a Antibody, clone TS2/7 (RPE)   

Anti-Human CD49a Antibody, clone TS2/7 (Biotin)

Mouse Anti-Human Monoclonal Antibody

     
  • FC - Anti-Human CD49a Antibody, clone TS2/7 (Biotin) ABD12029
    Staining of HeLa cells with Mouse anti Human CD49a
  • FC - Anti-Human CD49a Antibody, clone TS2/7 (Biotin) ABD12029
    Staining of HeLa cells with Mouse anti Human CD49a
  • FC - Anti-Human CD49a Antibody, clone TS2/7 (Biotin) ABD12029
    Staining of HeLa cells with Mouse anti Human CD49a: Alexa Fluor® 488
  • FC - Anti-Human CD49a Antibody, clone TS2/7 (Biotin) ABD12029
    Staining of HeLa cells with Mouse anti Human CD49a:FITC
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC
Primary Accession P56199
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names TS2/7
Calculated MW 130848 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Human CTL line directed against HLA-DR.
Shelf Life 12 months from date of reconstitution.
Gene ID 3672
Other Names Integrin alpha-1, CD49 antigen-like family member A, Laminin and collagen receptor, VLA-1, CD49a, ITGA1
Target/Specificity Mouse anti-Human CD49a antibody, clone TS2/7 recognizes the human alpha 1 integrin sub-unit, which forms the VLA-1 heterodimer in association with the beta 1 integrin. VLA-1 is a receptor for collagen and laminin, and is expressed by chronically activated T cells, melanoma cells and smooth muscle cells.Mouse anti-Human CD49a antibody, clone TS2/7 has been reported as being suitable for use in Western Blotting.Mouse anti-Human CD49a antibody, clone TS2/7 is routinely tested in flow cytometry using HeLa cells.
Preservative & Stabilisers 0.09% Sodium Azide; 1% Bovine Serum Albumin
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD49a Antibody, clone TS2/7 (Biotin) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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References

1. Hemler, M.E. et al. (1984) Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines
J. Immunol. 132: 3011. 2. Hemler, M. E. et al. (1985) Biochemical characterization of VLA-1 and VLA-2. Cell surface heterodimers on activated T cells
J. Biol. Chem. 260: 15246-15252. 3. Hafler, D. A. et al. (1985) Investigation of in vivo activated T cells in multiple sclerosis and inflammatory central nervous system diseases.
Clin. Immunol. Immunopathol. 37: 163-171. 4. Klemmt, P.A. et al. (2007) Endometrial cells from women with endometriosis have increased adhesion and proliferative capacity in response to extracellular matrix components: towards a mechanistic model for endometriosis progression.
Hum Reprod. 22: 3139-47. 5. Berry, P.A. et al. (2011) The calcium sensor STIM1 is regulated by androgens in prostate stromal cells.
Prostate. 71: 1646-55. 6. Elshaw, S.R. et al. (2001) A comparison of ocular melanocyte and uveal melanoma cell invasion and the implication of alpha1beta1, alpha4beta1 and alpha6beta1 integrins.
Br J Ophthalmol. 85: 732-8. 7. Cervar-Zivkovic, M. et al. (2011) Endothelin-1 Stimulates Proliferation of First-Trimester Trophoblasts via the A- and B-Type Receptor and Invasion via the B-Type Receptor.
J Clin Endocrinol Metab. 96: 3408-15. 8. Klemmt, P.A. et al. (2007) Endometrial cells from women with endometriosis have increased adhesion and proliferative capacity in response to extracellular matrix components: towards a mechanistic model for endometriosis progression.
Hum Reprod. 22: 3139-47. 9. Kaneko, Y. et al. (2012) Integrin a1/ß1 and a2/ß1 as a receptor for IgA1 in human glomerular mesangial cells in IgA nephropathy.
Int Immunol. 24: 219-32.

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Cat# ABD12029
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