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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Human CD21 Antibody, clone LB21 (RPE)   

Anti-Human CD21 Antibody, clone LB21

Mouse Anti-Human Monoclonal Antibody

  • IHC - Anti-Human CD21 Antibody, clone LB21  ABD12033
    Immunoperoxidase staining of human spleen cryosection using Mouse ati Human CD21 antibody followed by HISTAR detection system. High power
  • IHC - Anti-Human CD21 Antibody, clone LB21  ABD12033
    Immunoperoxidase staining of human tonsil cryosection using Mouse ati Human CD21 antibody followed by HISTAR detection system. High power
  • FC - Anti-Human CD21 Antibody, clone LB21  ABD12033
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD21
  • IF - Anti-Human CD21 Antibody, clone LB21  ABD12033
    Immunofluorescence staining of human tonsil cryosection with Mouse anti Human CD11b antibody, clone ICRF44 , red in A and Mouse anti Human CD21 , green in B. C is the merged image with nuclei counterstained blue using DAPI. medium power
  • IF - Anti-Human CD21 Antibody, clone LB21  ABD12033
    Immunofluorescence image of human tonsil cryosection stained with Sheep anti Human LOX-1 antibody in red and with Mouse anti Human CD21 antibody in red. Nuclei are stained blue using DAPI. Merged image on right
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P20023
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names LB21
Calculated MW 112916 Da
Additional Information
Other Species Sh,Mink,B,Ga,Cat
Purification Purified IgG prepared by ion exchange chromotography
Immunogen Human IM9 cell line.
Shelf Life 18 months from date of despatch.
Gene ID 1380
Other Names Complement receptor type 2, Cr2, Complement C3d receptor, Epstein-Barr virus receptor, EBV receptor, CD21, CR2, C3DR
Target/Specificity Mouse anti-Human CD21 antibody, clone LB21 recognizes the human Complement receptor type 2, also known as CD21 or the Epstein-Barr virus receptor. CD21 is a ~14 kDa cell surface glycoprotein expressed by mature B cells and by follicular dendritic cells. The molecule acts as a receptor for complement components C3d, C3dg and iC3b, as well as for Epstein Barr Virus. It forms part of a large signal transduction complex in association with CD19.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD21 Antibody, clone LB21 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Furukawa, Y. et al. (2000) Frequent reversible membrane damage in peripheral blood B cells in human T cell lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Clin Exp Immunol. 120 (2): 307-16. 2. Griebel, P.J. et al. (2007) Cross-reactivity of mAbs to human CD antigens with sheep leukocytes.
Vet Immunol Immunopathol. 119: 115-22. 3. Aasted, B. et al. (2007) Reactivity of monoclonal antibodies to human CD antigens with cells from mink.
Vet Immunol Immunopathol. 119: 27-37. 4. Sopp, P. et al. (2007) Cross-reactivity of mAbs to human CD antigens with cells from cattle.
Vet Immunol Immunopathol. 119: 106-14. 5. Davis, W.C. et al. (2007) Use of flow cytometry to identify monoclonal antibodies that recognize conserved epitopes on orthologous leukocyte differentiation antigens in goats, llamas, and rabbits.
Vet Immunol Immunopathol. 119: 123-30. 6. Aichem, A. et al. (2006) Redox regulation of CD21 shedding involves signaling via PKC and indicates the formation of a juxtamembrane stalk.
J Cell Sci. 119: 2892-902. 7. Angel, C.E. et al. (2009) Distinctive localization of antigen-presenting cells in human lymph nodes.
Blood. 113: 1257-67. 8. Sengstake, S. et al. (2006) CD21 and CD62L shedding are both inducible via P2X7Rs.
Int Immunol. 18: 1171-8. 9. Clutterbuck, E.A. et al. (2012) Pneumococcal conjugate and plain polysaccharide vaccines have divergent effects on antigen-specific B cells.
J Infect Dis. 205: 1408-16. 10. Meister, R.K. et al. (2007) Progress in the discovery and definition of monoclonal antibodies for use in feline research.
Vet Immunol Immunopathol. 119: 38-46. 11. Damgaard, B.M. et al. (2012) The effects of feed restriction on physical activity, body weight, physiology, haematology and immunology in female mink.
Res Vet Sci. 93: 936-42. 12. Stachowiak, B. & Weingartl, H.M. (2012) Nipah virus infects specific subsets of porcine peripheral blood mononuclear cells.
PLoS One. 7 (1): e30855.

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Cat# ABD12033
(40 western blots)
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