|Purification||Purified IgM prepared by ion exchange chromatography|
|Immunogen||Human neuroblastoma cells.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti-Human CD57 antibody, clone TB01 recognizes CD57, also known as HNK-1, an oligosaccharide antigenic determinant present on a variety of polypeptides, lipids and chondroitin sulphate proteoglycans. Its function is poorly understood. CD57 is present on a subset of NK and T cells.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or -20℃.|
|Precautions||Anti-Human CD57 Antibody, clone TB01 (FITC) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Funaro, A. et al. (1995) Epitope analysis of human CD57 by means of a panel of newly-generated high-affinity murine monoclonal antibodies.In Leucocyte Typing V: White Cell Differentiation Antigens. 2. Funaro, A. et al. (1995) Human CD57, a link molecule between leucocyte and neural cells.In: Leucocyte Typing V: White Cell Differentiation Antigens. 3. Slyker, J.A. et al. (2011) Phenotypic Characterization of HIV-Specific CD8 T Cells during Early and Chronic Infant HIV-1 Infection.PLoS One. 6: e20375. 4. Cerroni, L. et al. (2004) In: An Illustrated Guide to Skin Lymphoma: Second Edition.
Blackwell Publishing. Oxford. UKISBN 104051-1376-6 5. Nunes, C. et al. (2012) Expansion of a CD8+PD-1+ Replicative Senescence Phenotype in Early Stage CLL Patients Is Associated with Inverted CD4:CD8 Ratios and Disease Progression.Clin Cancer Res. 18: 678-87. 6. Hutnick, N.A. et al. (2010) Vaccination with Ad5 Vectors Expands Ad5-Specific CD8+ T Cells without Altering Memory Phenotype or FunctionalityPLoS One. 5: e14385. 7. Khan, N. et al. (2002) Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals.J Immunol. 169: 1984-92. 8. Alejenef, A. et al. (2014) Cytomegalovirus drives Vd2neg ?d T cell inflation in many healthy virus carriers with increasing age.Clin Exp Immunol. 176 (3): 418-28. 9. Frahm, M. et al. (2012) CD4+CD8+ T cells represent a significant portion of the anti-HIV T cell response to acute HIV infection.J Immunol. 188: 4289-96. 10. Wang, Y. et al. (2009) Characteristics of expanded CD4+CD28null T cells in patients with chronic hepatitis B.Immunol Invest. 38: 434-46. 11. Lim, H.W. and Kim, C.H. (2007) Loss of IL-7 receptor alpha on CD4+ T cells defines terminally differentiated B cell-helping effector T cells in a B cell-rich lymphoid tissue.J Immunol. 179: 7448-56. 12. Björkström, N.K. et al. (2012) CD8 T cells express randomly selected KIRs with distinct specificities compared with NK cells.Blood. 120: 3455-65. 13. Slyker, J.A. et al. (2012) The impact of HIV-1 infection and exposure on natural killer (NK) cell phenotype in Kenyan infants during the first year of life.Front Immunol. 3: 399. 14. Perlingeiro Beltrame, M. et al. (2014) Immune reconstitution in patients with Fanconi anemia after allogeneic bone marrow transplantation.Cytotherapy. 16: 976-89.
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