|Application ||FC, IP|
|Purification||Purified IgG prepared by affinity chromatography on Protein G.|
|Immunogen||Affinity purified murine T cell receptor.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Hamster anti-mouse TCR α/β, clone H57-597, recognises the β-chain of the murine α/β T cell receptor and does not show any reactivity to TCRγ/δ (Gascoigne, N., 1990).Clone H57-597 has been reported to activate T-cells in immobilised form (Kubo, R. et al., 1989) and has also been used for in vivo cell depletion (van der Heyde, H. et al., 1995andSkeen, M. & Ziegler, H., 1993). Removal of sodium azide is recommended prior to using this clone in functional assays. AbD Serotec recommend the Slide-A-Lyzer® Dialysis Cassette for this purpose.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse TCR alpha/beta beta Chain Antibody, clone H57-597 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Kubo, R.T. et al. (1989) Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors.J Immunol. 142 (8): 2736-42. 2. Goodman, T. & Lefrancois, L. (1989) Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function.J Exp Med. 170 (5): 1569-81. 3. Gascoigne, N.R. (1990) Transport and secretion of truncated T cell receptor beta-chain occurs in the absence of association with CD3.J Biol Chem. 265 (16): 9296-301. 4. van der Heyde, H.C. et al. (1995) Gamma delta T cells function in cell-mediated immunity to acute blood-stage Plasmodium chabaudi adami malaria.J Immunol. 154 (8): 3985-90. 5. Skeen, M.J. & Ziegler, H.K. (1993) Induction of murine peritoneal gamma/delta T cells and their role in resistance to bacterial infection.J Exp Med. 178 (3): 971-84. 6. Nilsson, I.A. et al. (2011) Evidence of hypothalamic degeneration in the anorectic anx/anx mouse.Glia. 59 (1): 45-57.
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