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Anti-Human CD95 Antibody, clone LOB 3/17

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti-Human CD95 Antibody, clone LOB 3/17  ABD12077
    Staining of HUT78 T cell line with Mouse anti Human CD95:FITC
  • FC - Anti-Human CD95 Antibody, clone LOB 3/17  ABD12077
    Staining of human peripheral blood granulocytes with Mouse anti Human CD95:Alexa Fluor® 647
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P25445
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names LOB 3/17
Calculated MW 37732 Da
Additional Information
Other Species Rh
Purification Purified IgG prepared by affinity chromatography on Protein A
Immunogen Fusion protein comprising extracellular domain of human Fas linked to human Fc.
Shelf Life 18 months from date of despatch.
Gene ID 355
Other Names Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, CD95, FAS, APT1, FAS1, TNFRSF6
Target/Specificity Mouse anti-Human CD95 antibody, clone LOB 3/17 recognizes the human CD95 cell surface antigen, a 40-50kDa glycoprotein expressed by activated T and B cells, NK cells and thymocytes.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD95 Antibody, clone LOB 3/17 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Mesdaghi, M. et al. (2010) Natural Killer Cells in Allergic Rhinitis Patients and Nonatopic Controls.
Int Arch Allergy Immunol. 153: 234-38. 2. Ximeri, M. et al.. (2010) Effect of lenalidomide therapy on hematopoiesis of patients with myelodysplastic syndrome associated with chromosome 5q deletion.
Haematologica. 95: 406-14. 3. Aref, S. et al. (2004) Accelerated neutrophil apoptosis in neutropenic patients with hepatosplenic schistosomiasis is induced by serum Fas ligand.
Hematol. J. 5: 434-9. 4. Welsh, J.P. et al.(2004)In vitro effects of interferon-gamma and tumor necrosis factor-alpha on CD34+ bone marrow progenitor cells from aplastic anemia patients and normal donors.
Hematol J. 5: 39-46. 5. Wethkamp, N. et al. (2011) Daxx-{beta} and Daxx-{gamma}, Two Novel Splice Variants of the Transcriptional Co-repressor Daxx.
J Biol Chem. 286: 19576-88. 6. Chen, J.Y. et al. (2003) TNF-alpha renders human peritoneal mesothelial cells sensitive to anti-Fas antibody-induced apoptosis.
Nephrol Dial Transplant. 18: 1741-7. 7. Papadaki, H.A. et al. (2002) Bone marrow progenitor cell reserve and function and stromal cell function are defective in rheumatoid arthritis: evidence for a tumor necrosis factor alpha-mediated effect.
Blood. 99: 1610-9. 8. Mavroudi, I. et al. (2011) The CD40/CD40 ligand interactions exert pleiotropic effects on bone marrow granulopoiesis.
J Leukoc Biol. 89: 771-83. 9. Pyrovolaki, K. et al. (2009) Increased expression of CD40 on bone marrow CD34+ hematopoietic progenitor cells in patients with systemic lupus erythematosus: contribution to Fas-mediated apoptosis.
Arthritis Rheum. 60: 543-52. 10. Boula, A. et al. (2006) Effect of cA2 anti-tumor necrosis factor-alpha antibody therapy on hematopoiesis of patients with myelodysplastic syndromes.
Clin Cancer Res. 12: 3099-108. 11. Papadaki, H.A. et al. (2005) Normal bone marrow hematopoietic stem cell reserves and normal stromal cell function support the use of autologous stem cell transplantation in patients with multiple sclerosis.
Bone Marrow Transplant. 36: 1053-63.1. Paulsen, M. and Janssen, O. (2011) Pro- and anti-apoptotic CD95 signaling in T cells.
Cell Commun Signal. 9:7.

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$ 323.00
$ 56.00
Cat# ABD12077
3 Formats Available
Availability: 5-7days
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