|Calculated MW||22517 Da|
|Purification||Purified IgG prepared by affinity chromatography|
|Immunogen||Murine dendritic epidermal Y245 cell line|
|Shelf Life||6 months from date of reconstitution.|
|Other Names||Early activation antigen CD69, CD69, Cd69|
|Target/Specificity||Hamster anti-Mouse CD69 antibody, clone H1.2F3 recognizes the murine CD69 cell surface antigen, an 85kDa dimeric glycoprotein. CD69 is expressed rapidly on the surface of T cells, B cells and NK cells following activation.|
|Preservative & Stabilisers||0.09% Sodium Azide; Stabilizing agent|
|Storage||Storage at +4ºC. DO NOT FREEZE.|
|Precautions||Anti-Mouse CD69 Antibody, clone H1.2F3 (RPE-CY5) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Yokoyama,W.M. et al. (1988) Characterization of a cell surface - expressed disulfide-linked dimer involved in murine T cell activation.J. Immunol. 141: 369-376. 2. Hickman, H.D. et al. (2008) Direct priming of antiviral CD8+ T cells in the peripheral interfollicular region of lymph nodes.Nat Immunol. 9: 155-65. 3. Chalifour, A. et al. (2004) Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin production.Blood. 104: 1778-83. 4. Cohen-Sfady, M. et al. (2005) Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway.J Immunol. 175: 3594-602. 5. Iwashiro, M. et al. (2001) Immunosuppression by CD4+ regulatory T cells induced by chronic retroviral infection.Proc Natl Acad Sci U S A. 98: 9226-30. 6. Karrer, U. et al. (2003) Memory inflation: continuous accumulation of antiviral CD8+ T cells over time.J Immunol. 170: 2022-9. 7. Kvakan, H. et al. (2009) Regulatory T cells ameliorate angiotensin II-induced cardiac damage.Circulation. 119: 2904-12. 8. Marshall-Clarke, S. et al. (2003) A differential requirement for phosphoinositide 3-kinase reveals two pathways for inducible upregulation of major histocompatibility complex class II molecules and CD86 expression by murine B lymphocytes.Immunology. 109: 102-8. 9. Zajac, A.J. et al. (1998) Viral immune evasion due to persistence of activated T cells without effector function.J Exp Med. 188: 2205-13. 10. Everitt, A.R. et al. (2012) IFITM3 restricts the morbidity and mortality associated with influenza.Nature. 484: 519-23.
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