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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Mouse CD86 Antibody, clone RMMP-2    

Anti-Mouse CD86 Antibody, clone RMMP-2 (FITC)

Rat Anti-Mouse Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P42082
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names RMMP-2
Calculated MW 34666 Da
Additional Information
Purification Purified IgG prepared by ion exchange chromatography.
Shelf Life 18 months from date of despatch.
Gene ID 12524
Other Names T-lymphocyte activation antigen CD86, Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1, CD86, Cd86
Target/Specificity Rat anti-Mouse CD86 antibody, clone RMMP-2 recognizes the murine CD86 cell surface antigen, also known as Activation B7-2 antigen or Early T-cell costimulatory molecule 1. CD86 is a 286 amino acid ~35 kDa single pass type type I transmembrane glycoprotein acting as a receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production.CD86 along with CD80 acts as a cell attachment receptor for group B adenoviruses (Shortet al.2006).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin
Storage Store at +4℃ or -20℃.
PrecautionsAnti-Mouse CD86 Antibody, clone RMMP-2 (FITC) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Tang, C. et al. (2001) Th type 1-stimulating activity of lung macrophages inhibits Th2-mediated allergic airway inflammation by an IFN-gamma-dependent mechanism.
J Immunol. 166 (3): 1471-81. 2. Cohen-Sfady, M. et al. (2005) Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway.
J Immunol. 175 (6): 3594-602. 3. Mercier, S. et al. (2002) Distinct roles of adenovirus vector-transduced dendritic cells, myoblasts, and endothelial cells in mediating an immune response against a transgene product.
J Virol. 76 (6): 2899-911. 4. Greicius, G. et al. (2004) Microvilli structures on B lymphocytes: inducible functional domains?
Int Immunol. 16: 353-64. 5. Sireci, G. et al. (2009) A continuous infusion of a minor histocompatibility antigen-immunodominant peptide induces a delay of male skin graft rejection.
Immunobiology. 214: 703-11. 6. Vliegen, I. et al. (2004) Murine cytomegalovirus infection directs macrophage differentiation into a pro-inflammatory immune phenotype: implications for atherogenesis
Microbes Infect. 6: 1056-62. 7. Wang, R. et al. (2008) GAD-IgG-inducing CD4+Foxp3+Treg cells suppressing diabetes are involved in the increasing ratio of CD80+:CD86+ CELLS in NOD mice.
Arch Med Res. 39 (3): 299-305. 8. Mohan, J. et al. (2005) Skin-derived dendritic cells acquire and degrade the scrapie agent following in vitroexposure.
Immunology. 116: 122-33.

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Cat# ABD12088
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