|Calculated MW||34666 Da|
|Purification||Purified IgG prepared by ion exchange chromatography.|
|Shelf Life||18 months from date of despatch.|
|Other Names||T-lymphocyte activation antigen CD86, Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1, CD86, Cd86|
|Target/Specificity||Rat anti-Mouse CD86 antibody, clone RMMP-2 recognizes the murine CD86 cell surface antigen, also known as Activation B7-2 antigen or Early T-cell costimulatory molecule 1. CD86 is a 286 amino acid ~35 kDa single pass type type I transmembrane glycoprotein acting as a receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production.CD86 along with CD80 acts as a cell attachment receptor for group B adenoviruses (Shortet al.2006).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or -20℃.|
|Precautions||Anti-Mouse CD86 Antibody, clone RMMP-2 (FITC) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Tang, C. et al. (2001) Th type 1-stimulating activity of lung macrophages inhibits Th2-mediated allergic airway inflammation by an IFN-gamma-dependent mechanism.J Immunol. 166 (3): 1471-81. 2. Cohen-Sfady, M. et al. (2005) Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway.J Immunol. 175 (6): 3594-602. 3. Mercier, S. et al. (2002) Distinct roles of adenovirus vector-transduced dendritic cells, myoblasts, and endothelial cells in mediating an immune response against a transgene product.J Virol. 76 (6): 2899-911. 4. Greicius, G. et al. (2004) Microvilli structures on B lymphocytes: inducible functional domains?Int Immunol. 16: 353-64. 5. Sireci, G. et al. (2009) A continuous infusion of a minor histocompatibility antigen-immunodominant peptide induces a delay of male skin graft rejection.Immunobiology. 214: 703-11. 6. Vliegen, I. et al. (2004) Murine cytomegalovirus infection directs macrophage differentiation into a pro-inflammatory immune phenotype: implications for atherogenesisMicrobes Infect. 6: 1056-62. 7. Wang, R. et al. (2008) GAD-IgG-inducing CD4+Foxp3+Treg cells suppressing diabetes are involved in the increasing ratio of CD80+:CD86+ CELLS in NOD mice.Arch Med Res. 39 (3): 299-305. 8. Mohan, J. et al. (2005) Skin-derived dendritic cells acquire and degrade the scrapie agent following in vitroexposure.Immunology. 116: 122-33.
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