|Application ||WB, IHC-P, IHC-F, FC, E|
|Calculated MW||83869 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Shelf Life||18 months from date of despatch.|
|Other Names||Myeloperoxidase, MPO, 22.214.171.124, Myeloperoxidase, 89 kDa myeloperoxidase, 84 kDa myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain, MPO|
|Target/Specificity||Mouse anti-Human Myeloperoxidase antibody, clone 2C7 recognizes human myeloperoxidase (MPO). MPO is an important component of azurophilic granules in neutrophils, being involved in microbicidal processes. The protein is a multimer of 2 heavy chains (55kD) and two light chains (15kD), the heavy chains being linked by a disulphide bond. Mouse anti-Human Myeloperoxidase antibody, clone 2C7 recognizes native MPO in Western blots, and the heavy chain following boiling of the sample. Mouse anti-Human Myeloperoxidase antibody, clone 2C7 also recognizes recombinant MPO in Western blots and weakly in ELISA.Mouse anti-Human Myeloperoxidase antibody, clone 2C7 may be of value in the study of myeloid cells and myeloid leukaemias by flow cytometry following cell permeablisation.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Myeloperoxidase Antibody, clone 2C7 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Audrain, M.A.P. et al. (1997) Anti-native and recombinant myeloperoxidase monoclonals and human autoantibodies.Clin. Exp. Immunol. 107: 127-134. 2. Patry, Y.C. et al. (1997) Difference in antigenic determinant profiles between human and rat myeloperoxidase.Clin ExpImmunol. 132: 505-8. 3. Zhang, N. et al. (2008) Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease.J Allergy Clin Immunol. 122: 961-8. 4. Sloane, A.J. et al. (2005) Proteomic analysis of sputum from adults and children with cystic fibrosis and from control subjects.Am J Respir Crit Care Med. 172: 1416-26. 5. Luo, B. et al. (2013) Immunopathology features of chronic rhinosinusitis in high-altitude dwelling Tibetans.Allergy Rhinol (Providence). 4: e69-76. 6. Behnen, M. et al. (2014) Immobilized immune complexes induce neutrophil extracellular trap release by human neutrophil granulocytes via Fc?RIIIB and Mac-1.J Immunol. 193 (4): 1954-65. 7. Villiers, E. et al. (2006) Identification of acute myeloid leukemia in dogs using flow cytometry with myeloperoxidase, MAC387, and a canine neutrophil-specific antibody.Vet Clin Pathol. 35 (1): 55-71.
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