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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Mouse CD8 Antibody, clone YTS169.4    

Anti-Mouse CD8 Antibody, clone YTS169.4

Rat Anti-Mouse Monoclonal Antibody

     
  • FC - Anti-Mouse CD8 Antibody, clone YTS169.4  ABD12113
    Staining of mouse spleen cells with Rat anti Mouse CD8 Alpha: Azide Free
  • IHC - Anti-Mouse CD8 Antibody, clone YTS169.4  ABD12113
    Immunoperoxidase staining of a mouse lymph node cryosection with Rat anti Mouse CD8 antibody, clone YTS169.4 followed by horseradish peroxidase conjugated Goat anti Rat IgG antibody . Medium power
  • FC - Anti-Mouse CD8 Antibody, clone YTS169.4  ABD12113
    Staining of mouse spleen with Rat anti Mouse CD8 Alpha: RPE
  • IHC-P - Anti-Mouse CD8 Antibody, clone YTS169.4  ABD12113
    Immunoperoxidase staining of a mouse lymph node cryosection with Rat anti Mouse CD8 antibody, clone YTS169.4 followed by horseradish peroxidase conjugated Goat anti Rat IgG antibody . High power
  • IHC - Anti-Mouse CD8 Antibody, clone YTS169.4  ABD12113
    Immunoperoxidase staining of a mouse lymph node cryosection with Rat anti Mouse CD8 antibody, clone YTS169.4 followed by horseradish peroxidase conjugated Goat anti Rat IgG antibody . Low power
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-F, FC
Primary Accession P01731
Other Accession P10300
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2b
Clone Names YTS169.4
Calculated MW 27456 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Shelf Life 12 months from date of reconstitution.
Gene ID 12525
Other Names T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, CD8a, Cd8a, Lyt-2, Lyt2
Target/Specificity Rat anti-Mouse CD8 antibody, clone YTS169.4 recognizes the murine CD8 cell surface antigen, expressed by a subset of T lymphocytes.Rat anti-Mouse CD8 antibody, clone YTS169.4 exhibits depleting activity when used in vivo.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse CD8 Antibody, clone YTS169.4 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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References

1. Cobbold, S.P. et al. (1990) The induction of skin graft tolerance in MHC-mismatched or primed recipients: primed T cells can be tolerized in the periphery with CD4 and CD8 antibodies.
Eur. J. Immunol. 20: 2747. 2. Bemelman, F. et al. (1998) Bone marrow transplantation induces either clonal deletion or infectious tolerance depending on the dose.
J. Immunol. 160: 2645-2648. 3. Cobbold, S.P. et al. (1984) Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo.
Nature 312: 548-551. 4. Wise, M.P. et al. (1998) Cutting Edge; Linked suppression of skin graft rejection can operate through indirect recognition.
J. Immunol. 161: 5813-5816. 5. Higgins, L. M. et al. (1999) Regulation of T-cell activation in vitroandin vivo by targeting the OX40 -OX40 Ligand Interaction: Amelioration of ongoing inflammatory bowel disease with an OX40 - IgG fusion protein, but not with an OX40 ligand - IgG fusion protein.
J. immunol. 162: 486 - 493. 6. Scotland, R.S. et al. (2011) Sex-differences in resident immune cell phenotype underlies more efficient acute inflammatory responses in female mice.
Blood. 118: 5918-27.

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