|Application ||IHC-F, FC, IP|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Bone cell suspension from SD rats.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti-Rat CD61 antibody, clone F11 recognizes the rat CD61 cell surface antigen, also known as the integrin b3 chain.CD61 is expressed by platelets, megakaryocytes and osteoclasts.Clone F11 has been shown to inhibit the in vitro attachment of osteoclasts to various proteins including vitronectin, fibrinogen and von Willebrand Factor (Sicket al.2009).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Rat CD61 Antibody, clone F11 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Helfrich, M. H. et al. (1992) Integrins on rat osteoclasts: characterization of two monoclonal antibodies (F4 and F11) to rat beta 3.J. Bone. Miner. Res. 7: 345-351. 2. Shankar, G. et al. (1993) Integrin receptor-mediated mobilisation of intranuclear calcium in rat osteoclasts.J. Cell. Sci. 105: 61-68. 3. Sick, E. et al. (2009) Activation of CD47 receptors causes histamine secretion from mast cells. Cell Mol Life Sci. 66: 1271-82. 4. Wang, Z. et al. (2015) Microparticle levels after arterial injury and NO therapy in diabetes.J Surg Res. pii: S0022-4804(15)00867-7
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