Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.Anti-Bovine Interleukin-4 Antibody, clone CC303
Mouse Anti-Bovine Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, E |
|---|---|
| Primary Accession | P30367 |
| Reactivity | Bovine |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Clone Names | CC303 |
| Calculated MW | 15119 Da |
| Other Species | Dog,Pig,Sh,Mustelid,Ga,Dolphin,Mink,Fin Whale,Hs |
|---|---|
| Purification | Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant |
| Shelf Life | 12 months from date of reconstitution. |
| Gene ID | 280824 |
| Other Names | Interleukin-4, IL-4, B-cell stimulatory factor 1, BSF-1, Lymphocyte stimulatory factor 1, IL4 |
| Target/Specificity | Mouse anti-Bovine Interleukin-4 antibody, clone CC303 recognizes bovine interleukin 4 |
| Preservative & Stabilisers | 0.09% Sodium Azide |
| Storage | Store at +4℃ or at -20 ℃. |
| Precautions | Anti-Bovine Interleukin-4 Antibody, clone CC303 is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abgent.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
1. Pedersen, L.G. et al. (2002) Identification of monoclonal antibodies that cross react with cytokines from different animal species. Vet. Immunol. Immunopathol. 88: 111 - 122. 2. Aasted, B. et al. (2002) Cytokine profiles in peripheral blood mononuclear cells and lymph node cells from piglets infected in utero with porcine reproductive and respiratory syndrome virus. Clin. Diagn. Lab. Immunol. 9: 1229 - 1234. 3. Nielsen, L. et al. (2009) Lymphotropism and host responses during acute wild-type canine distemper virusinfections in a highly susceptible natural host. J Gen Virol. 90: 2157-65. 4. Jaber, J.R. et al. (2010) Cross-reactivity of anti-human, anti-porcine and anti-bovine cytokine antibodies with cetacean tissues.J Comp Pathol. 143: 45-51. 5. Martel, C.J. & Aasted, B. (2009) Characterization of antibodies against ferret immunoglobulins, cytokines and CD markers.Vet Immunol Immunopathol. 132:109-15. 6. Fellman, C.L. et al. (2011) Cyclosporine A affects the in vitro expression of T cell activation-relatedmolecules and cytokines in dogs.Vet Immunol Immunopathol. 140: 175-80. 7. Araújo, M.S. et al. (2011) Immunological changes in canine peripheral blood leukocytes triggered by immunization with first or second generation vaccines against canine visceral leishmaniasis.Vet Immunol Immunopathol. 141: 64-75. 8. Jensen, P.V. et al. (2003) Cytokine profiles in adult mink infected with Aleutian mink disease parvovirus.J Virol. 77: 7444-51. 9. Papadogiannakis, E.I. et al. (2009) Determination of intracellular cytokines IFN-gamma and IL-4 in canine T lymphocytes by flow cytometry following whole-blood culture.Can J Vet Res. 73: 137-43. 10. Rutigliano, J.A. et al. (2008) Screening monoclonal antibodies for cross-reactivity in the ferret model of influenza infection.J Immunol Methods. 336: 71-7. 11. Wagner, B. et al. (2008) Characterization of monoclonal antibodies to equine interleukin-10 and detection of T regulatory 1 cells in horses.Vet Immunol Immunopathol. 122: 57-64. 12. Hamza, E. et al. (2007) Modulation of allergy incidence in icelandic horses is associated with a change in IL-4-producing T cells.Int Arch Allergy Immunol. 144: 325-37. 13. Costa-Pereira, C. et al. (2015) One-year timeline kinetics of cytokine-mediated cellular immunity in dogs vaccinated against visceral leishmaniasis.BMC Vet Res. 11 (1): 92. 14. Dean, G.S. et al. (2005) Minimum infective dose of Mycobacterium bovis in cattle.Infect Immun. 73 (10): 6467-71. 15. Araújo, M.S. et al. (2009) T-cell-derived cytokines, nitric oxide production by peripheral blood monocytes and seric anti-Leishmania (Leishmania) chagasi IgG subclass patterns following immunization against canine visceral leishmaniasis using Leishvaccine and Leishmune.Vaccine. 27 (7): 1008-17. 16. Yang, J. et al. (2012) Comparison of worm development and host immune responses in natural hosts of Schistosoma japonicum, yellow cattle and water buffalo.BMC Vet Res. 8: 25. 17. Taubert A et al. (2008) Antigen-induced cytokine production in lymphocytes of Eimeria bovis primary and challenge infected calves.Vet Immunol Immunopathol. 126 (3-4): 309-20. 18. Geherin, S.A. et al. (2013) Ovine skin-recirculating γδ T cells express IFN-γ and IL-17 and exit tissue independently of CCR7.Vet Immunol Immunopathol. 155 (1-2): 87-97. 19. Moreira, M. L. et al. (2016) Vaccination against canine leishmaniosis increases the phagocytic activity, nitric oxide production and expression of cell activation/migration molecules in neutrophils and monocytesVeterinary Parasitology. 15 Feb [Epub ahead of print]
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.
Ordering Information
Other Products
Shipping Information
