|Application ||IHC-P, FC, IP|
|Calculated MW||40983 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||T-end.1, a pMT transformed endothelial cell line|
|Shelf Life||18 months from date of despatch.|
|Other Names||Hematopoietic progenitor cell antigen CD34, CD34, Cd34|
|Target/Specificity||Rat anti-Mouse CD34 antibody, clone MEC14.7 recognizes the murine CD34 cell surface antigen, which is expressed by endothelial cells and by haematopoietic stem cells. This antibody recognizes a neuraminidase sensitive epitope. As in the human system, CD34 antibodies in the mouse demonstrate slightly different staining patterns depending on their fine specificity. Rat anti-Mouse CD34 antibody, clone MEC14.7 appears to recognize a subset of the stem cell population recognized by clone RAM34, and it is thought that this is due to differences in the epitope recognized by the two antibodies.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse CD34 Antibody, clone MEC14.7 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Garlanda, C. et al. (1997) Characterization of MEC14.7, a new monoclonal antibody recognising mouse CD34: a useful reagent for identifying and characterizing blood vessels and haematopoietic precursors.Eur. J. Cell Biol. 73: 368-377. 2. Winding, B. et al. (2002) Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice.Clin. Cancer Res. 8: 1932-1939. 3. Morison, N.B. et al. (2007) The long-term actions of etonogestrel and levonorgestrel on decidualized and non-decidualized endometrium in a mouse model mimic some effects of progestogen-onlycontraceptives in women.Reproduction. 133: 309-21. 4. Chen, L. et al. (2010) Roles of tetrahydrobiopterin in promoting tumor angiogenesis.Am J Pathol. 177: 2671-80. 5. Ager, E.I. et al. (2010) Targeting the angiotensin II type 2 receptor (AT2R) in colorectal liver metastases.Cancer Cell Int. 10: 19 6. Chabot, S. et al. (2011) A novel antiangiogenic and vascular normalization therapy targeted against human CD160 receptor.J Exp Med. 208: 973-86. 7. Chen, J. et al. (2011) Circulating endothelial progenitor cells and cellular membrane microparticles in db/db diabetic mouse: possible implications in cerebral ischemic damage.Am J Physiol Endocrinol Metab. 2011 Jul;301(1):E62-71. 8. Chen, J. et al. (2012) Transfusion of CXCR4-Primed Endothelial Progenitor Cells Reduces Cerebral Ischemic Damage and Promotes Repair in db/db Diabetic Mice.PLoS ONE 7(11): e50105.
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