|Calculated MW||109865 Da|
|Other Species||Cynomolgus Pr,B|
|Purification||Purified IgG prepared by affinity chromatography|
|Immunogen||MOLM-1 megakaryocyte cell line|
|Shelf Life||6 months from date of reconstitution.|
|Other Names||Mast/stem cell growth factor receptor Kit, SCFR, 188.8.131.52, Piebald trait protein, PBT, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, CD117, KIT, SCFR|
|Target/Specificity||Mouse anti-Human CD117 antibody, clone 104D2 recognizes the human CD117 cell surface antigen, a 145 kDa glycoprotein also known as c-kit. CD117 is expressed by some haematopoietic stem cells (approx. 70% of CD34+ve cells in normal bone marrow are CD117+ve), some acute myeloid leukaemias and by mast cells.Functionally CD117 is a receptor for stem cell factor, and has receptor tyrosine kinase activity.Mouse anti-Human CD117 antibody, clone 104D2 is non-neutralising.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD117 Antibody, clone 104D2 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Broudy, V.C. et al. (1998) Analysis of c-kit receptor dimerization by fluorescence resonance energy transfer.Blood 91: 898-906. 2. Yoshino, N. et al. (2000) Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of Cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Exp. Anim. 49: 97-110. 3. Jayapal, M. et al. (2006) Genome-wide gene expression profiling of human mast cells stimulated by IgE orFcepsilonRI-aggregation reveals a complex network of genes involved ininflammatory responses. BMC Genomics. 7: 210 - 26 4. Randall, V.A. et al. (2008) Stem cell factor/c-Kit signalling in normal and androgenetic alopecia hair follicles.J Endocrinol. 197: 11-23.
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