|Application ||WB, IHC-P, IF, FC, IP|
|Calculated MW||25809 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||OCI-LY8 cells aggregated by 5A6 (another CD81 antibody)|
|Shelf Life||18 months from date of despatch.|
|Other Names||CD81 antigen, 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1, Tetraspanin-28, Tspan-28, CD81, CD81, TAPA1, TSPAN28|
|Target/Specificity||Mouse anti-Human CD81 antibody, clone 1D6 recognizes human CD81, a 26kDa cell surface antigen also known as TAPA-1, and a member of the tetraspanin family.CD81 is widely expressed on human leucocytes and appears to be involved in a variety of cellular leucocytes including activation, proliferation and differentiation.Mouse anti-Human CD81 antibody, clone 1D6 is a potent CD81 reagent, induces homotypic adhesion and has powerful anti-proliferative effects.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD81 Antibody, clone 1D6 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Schick, M. R. and Levy, S. (1993) The TAPA-1 molecule is associated on the surface of B cells with HLA-DR molecules.J. Immunol. 151: 4090-4097. 2. Levy, S. et al. (1998) CD81 (TAPA-1): A molecule involved in signal transduction and cell adhesion in the immune system.Ann. Rev. Immunol. 16: 89-109. 3. Griebel, P.J. et al. (2007) Cross-reactivity of mAbs to human CD antigens with sheep leukocytes.Vet Immunol Immunopathol. 119: 115-22. 4. Welton, J.L. et al (2010) Proteomics analysis of bladder cancer exosomes. Mol Cell Proteomics. 9: 1324-38. 5. Davis, W.C. et al. (2007) Use of flow cytometry to identify monoclonal antibodies that recognize conserved epitopes on orthologous leukocyte differentiation antigens in goats, llamas, and rabbits.Vet Immunol Immunopathol. 119: 123-30. 6. Flint, M. et al. (1999) Characterization of hepatitis C virus E2 glycoprotein interaction with a putative cellular receptor, CD81.J Virol. 73:6235-44. 7. Parthasarathy, V. et al. (2009) Distinct roles for tetraspanins CD9, CD63 and CD81 in the formation of multinucleated giant cells.Immunology. 127: 237-48. 8. Rohlena, J. et al. (2009) Endothelial CD81 is a marker of early human atherosclerotic plaques and facilitates monocyte adhesion.Cardiovasc Res. 81: 187-96.
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