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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Human CD11a Antibody, clone 38    

Anti-Human CD11a Antibody, clone 38

Mouse Anti-Human Monoclonal Antibody

     
  • FC - Anti-Human CD11a Antibody, clone 38  ABD12127
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD11a:Alexa Fluor® 647
  • FC - Anti-Human CD11a Antibody, clone 38  ABD12127
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD11a:Biotin
  • FC - Anti-Human CD11a Antibody, clone 38  ABD12127
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD11a:RPE
  • FC - Anti-Human CD11a Antibody, clone 38  ABD12127
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD11a:FITC
  • FC - Anti-Human CD11a Antibody, clone 38  ABD12127
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD11a:Azide Free
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-F, IF, FC, IP
Primary Accession P20701
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names 38
Calculated MW 128770 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Shelf Life 18 months from date of despatch.
Gene ID 3683
Other Names Integrin alpha-L, CD11 antigen-like family member A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain, CD11a, ITGAL, CD11A
Target/Specificity Mouse anti-Human CD11a antibody, clone 38 recognizes the integrin alphaL subunit, a 180 kDa glycoprotein expressed by all human leucocytes. CD11a is involved in cell-cell adhesion processes and binds to ICAM-1, 2 and 3.Mouse anti-Human CD11a antibody, clone 38 neutralizes CD11a mediated adhesion.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD11a Antibody, clone 38 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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References

1. Dransfield, I. & Hogg, N. (1989) Regulated expression of Mg2+ binding epitope on leukocyte integrin alpha subunits.
EMBO J. 8 (12): 3759-65. 1. Daehn, I.S. (2010) T-lymphocyte-induced, fas-mediated apoptosis is associated with early keratinocyte differentiation.
Exp Dermatol. 19: 372-80. 2. Berg, L.P. et al. (2002) Functional consequences of noncognate interactions between CD4+ memory T lymphocytes and the endothelium.
J Immunol. 168 (7): 3227-34. 3. Foster, G.R. et al. (2004) IFN-alpha subtypes differentially affect human T cell motility.
J Immunol. 173: 1663-70. 4. Evans, B.J. et al. (2006) Shedding of lymphocyte function-associated antigen-1 (LFA-1) in a human inflammatory response.
Blood. 107: 3593-9. 5. Suchard, S.J. et al. (2010) An LFA-1 (alphaLbeta2) small-molecule antagonist reduces inflammation and joint destruction in murine models of arthritis.
J Immunol. 184: 3917-26. 6. Porter, J.C. and Hall, A. (2009) Epithelial ICAM-1 and ICAM-2 regulate the egression of human T cells across the bronchial epithelium.
FASEB J. 23: 492-502.

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Cat# ABD12127
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