Register or Login
All
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Microbiology   >   Anti-Mouse MARCO Antibody, clone ED31 (RPE)   

Anti-Mouse MARCO Antibody, clone ED31

Rat Anti-Mouse Monoclonal Antibody

     
  • IHC - Anti-Mouse MARCO Antibody, clone ED31  ABD12128
    Immunoperoxidase staining of a mouse lymph node cryosection with Rat anti Mouse MARCO antibody, clone ED31 followed by horseradish peroxidase conjugated Goat anti Rat IgG antibody . High power
  • IF - Anti-Mouse MARCO Antibody, clone ED31  ABD12128
    Immunofluorescence staining of a mouse lymph node cryosection with Rat anti Mouse MARCO antibody, clone ED31 , green in A and Rat anti Mouse CD8 antibody, clone YTS105.18 , red in B. C is the merged image wiith nuclei counterstained blue using DAPI. high power
  • IF - Anti-Mouse MARCO Antibody, clone ED31  ABD12128
    Immunofluorescence staining of a mouse lymph node cryosection with Rat anti Mouse MARCO antibody, clone ED31 , green in A and Rat anti Mouse CD8 antibody, clone YTS105.18 , red in B. C is the merged image wiith nuclei counterstained blue using DAPI. Low power
  • IHC-P - Anti-Mouse MARCO Antibody, clone ED31  ABD12128
    Immunoperoxidase staining of a mouse lymph node cryosection with Rat anti Mouse MARCO antibody, clone ED31 followed by horseradish peroxidase conjugated Goat anti Rat IgG antibody . Medium power
  • FC - Anti-Mouse MARCO Antibody, clone ED31  ABD12128
    Staining of mouse peritoneal macrophages with Rat anti Mouse MARCO: FITC
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-F, IF, FC
Primary Accession Q60754
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG1
Clone Names ED31
Calculated MW 52730 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen CHO cells expressing mouse MARCO
Shelf Life 18 months from date of despatch.
Gene ID 17167
Other Names Macrophage receptor MARCO, Macrophage receptor with collagenous structure, Marco
Target/Specificity Rat anti-Mouse MARCO antibody, clone ED31 recognizes the murine cell surface antigen designated MARCO (Macrophage receptor with collagenous structure), which is a member of the class A scavenger receptor family.MARCO is expressed by distinct populations of macrophages in the spleen and lymph nodes, but is rapidly induced on macrophages in other tissues (e.g. Liver Kupffer cells) during infection or LPS treatment.Rat anti-Mouse MARCO antibody, clone ED31 binds to the C-terminal cysteine rich domain of MARCO, and has been shown to block ligand binding.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse MARCO Antibody, clone ED31 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to
info@abgent.com, and receive a free "I Love Antibodies" mug.

References

1. van der Laan, L.J. et al. (1999) Regulation and functional involvement of macrophage scavenger receptor MARCO in clearance of bacteria in vivo.
J Immunol. 162 (2): 939-47. 2. van der Laan, L.J. et al. (1997) Macrophage scavenger receptor MARCO: in vitroandin vivo regulation and involvement in the anti-bacterial host defense.
Immunol Lett. 57 (1-3): 203-8. 3. Dioszeghy, V. et al. (2008) 12/15-Lipoxygenase regulates the inflammatory response to bacterial products in vivo.
J Immunol. 181: 6514-24. 4. Devey, L. et al. (2009) Tissue-resident macrophages protect the liver from ischemia reperfusion injury via a heme oxygenase-1-dependent mechanism.
Mol Ther. 17: 65-72. 5. Hsu, K.M. et al. (2009) Murine cytomegalovirus displays selective infection of cells within hours after systemic administration.
J Gen Virol. 90: 33-43. 6. Kang, Y.S. et al. (2004) The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide of Streptococcus pneumoniae in the marginal zone of mouse spleen.
Proc Natl Acad Sci U S A. 101: 215-20. 7. Karlsson, M.C. et al. (2003) Macrophages control the retention and trafficking of B lymphocytes in the splenic marginal zone.
J Exp Med. 198: 333-40. 8. Taylor, P.R. et al. (2004) Development of a specific system for targeting protein to metallophilic macrophages.
Proc Natl Acad Sci U S A. 101: 1963-8. 9. Alarcón, R. et al. (2005) Expression of scavenger receptors in glial cells. Comparing the adhesion of astrocytes and microglia from neonatal rats to surface-bound beta-amyloid.
J Biol Chem. 280: 30406-15. 10. Anthony, R.M. et al. (2008) Identification of a receptor required for the anti-inflammatory activity of IVIG.
Proc Natl Acad Sci U S A. 105: 19571-8. 11. Beamer, C.A. and Holian. A. (2008) Silica suppresses Toll-like receptor ligand-induced dendritic cell activation.
FASEB J. 22: 2053-63. 12. Granucci, F. et al. (2003) The scavenger receptor MARCO mediates cytoskeleton rearrangements in dendritic cells and microglia.
Blood. 102: 2940-7. 13. Mattsson, J. et al. (2011) Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.
J Immunol. 187: 3641-52. 14. Fukui Y et al. (2013) Effect of Lactobacillus brevis KB290 on the cell-mediated cytotoxic activity of mouse splenocytes: a DNA microarray analysis.
Br J Nutr. 110 (9): 1617-29.

FeedBack
Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at tech@abgent.com.

Cat# ABD12128
Size:
Quantity:
Availability: Inquire
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Crown-Flash18
Terms & Conditions