|Clone Names||604B5 2E11|
|Calculated MW||109179 Da|
|Purification||Purified IgG prepared by ion exchange chromatography|
|Immunogen||Raw 264 cells|
|Shelf Life||18 months from date of despatch.|
|Other Names||Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, CSF-1R, M-CSF-R, 188.8.131.52, Proto-oncogene c-Fms, CD115, Csf1r, Csfmr, Fms|
|Target/Specificity||Rat anti-Mouse CD115 antibody, clone 604B5 2E11 recognizes the murine CD115 cell surface antigen, also known as the M-CSF receptor and as c-fms.CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Rat anti-Mouse CD115 antibody, clone 604B5 2E11 has been shown to inhibit in vitro colony formation in response to M-CSF in both rats and mice.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Mouse CD115 Antibody, clone 604B5 2E11 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Shadduck, R.K. et al. (1996) Paradoxical stimulation of normal and leukemic rat hematopoiesis by monoclonal antibody to CSF-1 receptor.Exp Hematol. 24 (2): 314-7. 2. Gilmore, G.L. & Shadduck, R.K. (1995) Inhibition of day-12 spleen colony-forming units by a monoclonal antibody to the murine macrophage/monocyte colony-stimulating factor receptor.Blood. 85 (10): 2731-4. 3. MacDonald, K.P. et al. (2005) The colony-stimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion.J Immunol. 175 (3): 1399-405. 4. Buono, M. et al. (2010) Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development.J Exp Med. 207 (8): 1647-60. 5. Weingärtner, O. et al. (2011) Differential effects on inhibition of cholesterol absorption by plant stanol and plant sterol esters in apoE-/- mice.Cardiovasc Res. 90: 484-92. 6. Hayashi, Y. et al. (2010) Lumican is required for neutrophil extravasation following corneal injury and wound healing.J Cell Sci.123: 2987-95. 7. Herold, S. et al. (2008) Lung epithelial apoptosis in influenza virus pneumonia: the role of macrophage-expressed TNF-related apoptosis-inducing ligand.J Exp Med. 205: 3065-77. 8. Pillai, M.M. et al. (2009) Inducible transgenes under the control of the hCD68 promoter identifies mouse macrophages with a distribution that differs from the F4/80 - and CSF-1R-expressing populations.Exp Hematol. 37: 1387-92. 9. Sasmono, R.T. et al. (2007) Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.J Leukoc Biol. 82: 111-23.
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