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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Rat CD47 Antibody, clone OX-101 (RPE)   

Anti-Rat CD47 Antibody, clone OX-101

Mouse Anti-Rat Monoclonal Antibody

  • FC - Anti-Rat CD47 Antibody, clone OX-101  ABD12144
    Staining of Rat Spleen cells with Mouse anti Rat CD47:FITC
  • FC - Anti-Rat CD47 Antibody, clone OX-101  ABD12144
    Staining of Rat Spleen cells with Mouse anti Rat CD47:Alexa Fluor® 647
  • FC - Anti-Rat CD47 Antibody, clone OX-101  ABD12144
    Staining of Rat Spleen cells with Mouse anti Rat CD47:RPE
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P97829
Reactivity Rat
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names OX-101
Calculated MW 32995 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Rat thymocytes.
Shelf Life 18 months from date of despatch.
Gene ID 29364
Other Names Leukocyte surface antigen CD47, Integrin-associated protein, IAP, CD47, Cd47
Target/Specificity Mouse anti-Rat CD47 antibody, clone OX-101 recognizes the rat homologue of human CD47, also known as integrin associated protein (IAP). Rat CD47 is a 303 amino acid ӯ33 kDa multi pass transmembrane glycoprotein bearing a single V-type Ig-like domain and has been identified as the ligand for the rat signal regulatory protein, SIRP (Vernon-Wilsonet al.2000). Rat CD47 is expressed primarily by lymphocytes and macrophages but has also been detected at high levels on brain endothelial cells.Mouse anti-Rat CD47 antibody, clone OX-101 has been reported to block the interaction of CD47 and SIRP (Vernon-Wilsonet al.2000).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Rat CD47 Antibody, clone OX-101 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Vernon-Wilson, E. F. et al. (2000) CD47 is a ligand for rat macrophage membrane signal regulatory protein SIRP (OX41) and human SIRPalpha1.
Eur. J. Immunol. 30: 2130-2137. 2. de Vries, H.E. et al. (2002) Signal regulatory protein alpha - CD47 interactions are required for the transmigration of monocytes across cerebral endothelium.
J. Immunol. 168: 5832 - 5839. 3. Sick, E. et al. (2009) Activation of CD47 receptors causes histamine secretion from mast cells.
Cell Mol Life Sci. 66: 1271-82. 4. Barrès, C. et al. (2010) Galectin-5 is bound onto the surface of rat reticulocyte exosomes and modulates vesicle uptake by macrophages.
Blood. 115: 696-705. 5. Kurihara H et al. (2010) SIRP-alpha-CD47 system functions as an intercellular signal in the renal glomerulus.
Am J Physiol Renal Physiol. 299 (3): F517-27.

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Cat# ABD12144
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