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Anti-Human CD143 Antibody, clone 9B9

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti-Human CD143 Antibody, clone 9B9  ABD12153
    Staining of CHO cells transfected with human CD143 (ACE) with Mouse anti Human CD143: FITC
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P12821
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 9B9
Calculated MW 149715 Da
Additional Information
Other Species Ha,Pr,Rat,Cat
Purification Purified IgG prepared by affinity chromatography on Protein G.
Immunogen Human lung CD143 (Angiotensin converting enzyme)
Shelf Life 18 months from date of despatch.
Gene ID 1636
Other Names Angiotensin-converting enzyme, ACE, 3.2.1.-,, Dipeptidyl carboxypeptidase I, Kininase II, CD143, Angiotensin-converting enzyme, soluble form, ACE, DCP, DCP1
Target/Specificity Mouse anti-Human CD143 antibody, clone 9B9 recognizes human somatic CD143, also know as angiotensin - converting enzyme (ACE). CD143 exists in two forms, a ~170 kDa somatic form and a ~90 kDa germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.This antibody recognizes active ACE binding to an N-terminal domain epitope, different to that recognized by clone i2H5 (MCA2055).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD143 Antibody, clone 9B9 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Danilov, S. et al. (1994) Structure-function analysis of angiotensin I-converting enzyme using monoclonal antibodies. Selective inhibition of the amino-terminal active site.
J Biol Chem. 269 (43): 26806-14. 2. Metzger, R. et al. (2000) CD143 in the development of atherosclerosis.
Atherosclerosis. 150 (1): 21-31. 3. Danilov, S.M. et al. (1991) Lung is the target organ for a monoclonal antibody to angiotensin-converting enzyme.
Lab Invest. 64 (1): 118-24. 4. Ulrich, C. et al. (2011) Monocyte Angiotensin converting enzyme expression may be associated with atherosclerosis rather than arteriosclerosis in hemodialysis patients.
Clin J Am Soc Nephrol. 6: 505-11. 5. Danilov, S. et al. (1989) Radioimmunoimaging of lung vessels: an approach using indium-111-labeled monoclonal antibody to angiotensin-converting enzyme.
J Nucl Med. 30:1686-92. 6. Atochina, E. et al. (1998) Immunotargeting of catalase to ACE or ICAM-1 protects perfused rat lungs against oxidative stress.
Am J Physiol. 275:L806-17.

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Cat# ABD12153
(40 western blots)
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