|Application ||WB, FC, E|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Purified rCTLA-4hIg fusion protein.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti-Rat CD152 antibody, clone WKH203 recognizes rat CD152, also known as cytoxic-T-lymphocyte antigen-4 (CTLA-4), which is similar in structure to CD28 and also binds ligands CD80 and CD86. CD152 is expressed by activated T-lymphocytes and studies also suggest expression by regulatory T-lymphocytes (Lin and Hunig 2003).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Rat CD152 Antibody, clone WKH203 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Elflein, K. et al. (2003) Rapid recovery from T lymphopenia by CD28 superagonist therapyBlood. 102: 1764-1770. 2. Lin, C-H. and Hunig, T. (2003) Efficient expansion of regulatory T cells in vitroandin vivo with a CD 28 superagonist.Eur J. Immunol. 33: 626-638. 3. Almolda, B. et al. (2010) Activated microglial cells acquire an immature dendritic cell phenotype and may terminate the immune response in an acute model of EAE.J Neuroimmunol. 223:39-54.
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