|Application ||WB, IHC-F, IF, FC|
|Calculated MW||37557 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||HeLa cell transfectants expressing human BLTR.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Leukotriene B4 receptor 1, LTB4-R 1, LTB4-R1, Chemoattractant receptor-like 1, G-protein coupled receptor 16, P2Y purinoceptor 7, P2Y7, LTB4R, BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7|
|Target/Specificity||Mouse anti-Human BLTR antibody, clone 202/7B1 recognizes the human BLTR molecule, the leukotriene B4 receptor.BLTR is expressed by peripheral blood granulocytes and is important in the pro-inflammatory response.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human BLTR Antibody, clone 202/7B1 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Pettersson, A. et al. (2000) First generation monoclonal antibodies identifying the human leukotriene B receptor-1. Biochem. Biophys. Res. Commun. 279: 520 - 525. 2. Costa, M.F. et al. (2010) Leukotriene B4 mediates gammadelta T lymphocyte migration in response to diverse stimuli. J Leukoc Biol. 87: 323-32. 3. Islam, S.A. et al. (2006) The leukotriene B4 lipid chemoattractant receptor BLT1 defines antigen-primed T cells in humans.Blood. 107: 444-53. 4. Medoff, B.D. et al. (2005) BLT1-mediated T cell trafficking is critical for rejection and obliterative bronchiolitis after lung transplantation.J Exp Med. 202: 97-110. 5. Serezani, C.H. et al. (2009) FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions.Blood. 114: 3316-24. 6. Heller, E.A. et al. (2005) Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment.Circulation. 112: 578-86. 7. Thomas, S.Y. et al. (2007) Multiple chemokine receptors, including CCR6 and CXCR3, regulate antigen-induced T cell homing to the human asthmatic airway.J Immunol. 179: 1901-12. 8. Sabirsh, A. et al. (2005) Fluorescent leukotriene B4: potential applications.J Lipid Res. 46: 1339-46. 9. Loell, I. et al. (2012) Activated LTB4 pathway in muscle tissue of patients with polymyositis or dermatomyositis.Ann Rheum Dis. 72: 293-9. 10. Wang, L. et al. (2012) BLT1-Dependent Alveolar Recruitment of CD4+CD25+ Foxp3+ Regulatory T Cells is Important for Resolution of Acute Lung Injury.Am J Respir Crit Care Med.186: 989-98. 11. Laarman, A.J. et al.(2012)Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis.EMBO J. 31: 3607-19. 12. Dixit, N. et al. (2014) Leukotriene B4 activates intracellular calcium and augments human osteoclastogenesis.Arthritis Res Ther. 16: 496.
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