|Calculated MW||130159 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Hairy cell leukaemia cells.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Integrin alpha-E, HML-1 antigen, Integrin alpha-IEL, Mucosal lymphocyte 1 antigen, CD103, Integrin alpha-E light chain, Integrin alpha-E heavy chain, ITGAE|
|Target/Specificity||Mouse anti-Human CD103 antibody, clone LF61 recognizes the human CD103 cell surface antigen, a glycoprotein expressed by approximately 1% of peripheral blood lymphocytes, activated T lymphocytes and by hairy cell leukaemia cells. The antigen is also expressed by intraepithelial lymphocytes. It has recently been shown to be identical to the alpha E integrin.|
|Preservative & Stabilisers||0.09% Sodium Azide; Stabilizing agent|
|Storage||Storage at +4ºC. DO NOT FREEZE.|
|Precautions||Anti-Human CD103 Antibody, clone LF61 (RPE-CY5) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Flenghi, L. et al. (1990) LF61: a new monoclonal antibody directed against a trimeric molecule (150kD, 125kD, 105kD) associated with hairy cell leukaemia.Br. J. Haem. 76: 451-459. 2. Falini, B. et al. (1990) Selection of a panel of monoclonal antibodies for monitoring residual disease in peripheral blood and bone marrow of interferon-treated hairy cell leukaemia patients.Br. J. Haem. 76: 460-468. 3. Ling, K.L. et al. (2007) Modulation of CD103 expression on human colon carcinoma-specific CTL.J Immunol. 178: 2908-15. 4. Hadley, G.A. et al. (2001) CD103+ CTL accumulate within the graft epithelium during clinical renal allograft rejection.Transplantation. 72 (9): 1548-55.
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