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Anti-Human CD103 Antibody, clone LF61 (RPE-CY5)

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P38570
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names LF61
Calculated MW 130159 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Hairy cell leukaemia cells.
Shelf Life 18 months from date of despatch.
Gene ID 3682
Other Names Integrin alpha-E, HML-1 antigen, Integrin alpha-IEL, Mucosal lymphocyte 1 antigen, CD103, Integrin alpha-E light chain, Integrin alpha-E heavy chain, ITGAE
Target/Specificity Mouse anti-Human CD103 antibody, clone LF61 recognizes the human CD103 cell surface antigen, a glycoprotein expressed by approximately 1% of peripheral blood lymphocytes, activated T lymphocytes and by hairy cell leukaemia cells. The antigen is also expressed by intraepithelial lymphocytes. It has recently been shown to be identical to the alpha E integrin.
Preservative & Stabilisers 0.09% Sodium Azide; Stabilizing agent
Storage Storage at +4ºC. DO NOT FREEZE.
PrecautionsAnti-Human CD103 Antibody, clone LF61 (RPE-CY5) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Flenghi, L. et al. (1990) LF61: a new monoclonal antibody directed against a trimeric molecule (150kD, 125kD, 105kD) associated with hairy cell leukaemia.
Br. J. Haem. 76: 451-459. 2. Falini, B. et al. (1990) Selection of a panel of monoclonal antibodies for monitoring residual disease in peripheral blood and bone marrow of interferon-treated hairy cell leukaemia patients.
Br. J. Haem. 76: 460-468. 3. Ling, K.L. et al. (2007) Modulation of CD103 expression on human colon carcinoma-specific CTL.
J Immunol. 178: 2908-15. 4. Hadley, G.A. et al. (2001) CD103+ CTL accumulate within the graft epithelium during clinical renal allograft rejection.
Transplantation. 72 (9): 1548-55.

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Cat# ABD12181
(40 western blots)
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