|Application ||IHC-F, IF, FC, IP|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Rat alveolar macrophages.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti-Rat CD11c antibody, clone 8A2 recognizes the rat CD11c cell surface antigen, expressed by some myeloid cells and dendritic cells. Mouse anti-Rat CD11c antibody, clone 8A2 immunoprecipitates a 130-140/90 kDa heterodimer and modestly inhibits macrophage adherence on plastic (by around 20-30%).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Rat CD11c Antibody, clone 8A2 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Zilka, N. et al. (2009) Human misfolded truncated tau protein promotes activation of microglia and leukocyte infiltration in the transgenic rat model of tauopathy.J. Neuroimmunol. 209: 16-25. 2. Baba, T. et al . (2008) Rat CD4+CD8+ macrophages kill tumor cells through an NKG2D- and granzyme/perforin-dependent mechanism.J Immunol. 180: 2999-3006. 3. Baca Jones, C.C. et al. (2009) Rat cytomegalovirus infection depletes MHC II in bone marrow derived dendritic cells.Virology. 388: 78-90. 4. Bode, U. et al. (2008) Dendritic cell subsets in lymph nodes are characterized by the specific draining area and influence the phenotype and fate of primed T cells.Immunology. 123: 480-90. 5. Veelken, R. et al (2008) Autonomic renal denervation ameliorates experimental glomerulonephritis.J Am Soc Nephrol. 19: 1371-8.
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