|Application ||WB, IHC-F, IF, FC, IP|
|Calculated MW||202167 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Purified alpha6 beta4 integrin from A431 cells.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Integrin beta-4, GP150, CD104, ITGB4|
|Target/Specificity||Mouse anti-Human CD104 antibody, clone 450-9D recognizes the human beta4 integrin, also known as CD104. CD104 is a ~205 kDa glycoprotein which associates with the alpha6 integrin to form the alpha6/beta4 complex. CD104 is expressed on epithelial cells, Schwann cells and various tumor cell lines. Mouse anti-Human CD104 antibody, clone 450-9D recognizes an extracellular epitope on the CD104 molecule.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD104 Antibody, clone 450-9D is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Kennel, S.J. et al. (1990) Second generation monoclonal antibodies to the human integrin alpha 6 beta 4.Hybridoma. 9 (3): 243-55. 2. Barbaro,V. et al (2009) Reconstruction of a human hemicornea through natural scaffolds compatible with the growth of corneal epithelial stem cells and stromal keratocytes.Mol. Vis. 15: 2084-93 3. Martel, C.J. & Aasted, B. (2009) Characterization of antibodies against ferret immunoglobulins, cytokines and CD markers.Vet Immunol Immunopathol. 132:109-15. 4. Smith, K. et al. (2011) Mono- and tri-cationic porphyrin-monoclonal antibody conjugates: photodynamic activity and mechanism of action.Immunology. 132: 256-65. 5. Alam, H. et al. (2011) Loss of keratins 8 and 18 leads to alterations in a6ß4-integrin-mediated signalling and decreased neoplastic progression in an oral-tumour-derived cell line.J Cell Sci. 124: 2096-106.
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