|Application ||WB, IHC-F, FC|
|Calculated MW||126606 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||a6b4 integrin purified from A431 cells|
|Shelf Life||18 months from date of despatch.|
|Other Names||Integrin alpha-6, CD49 antigen-like family member F, VLA-6, CD49f, Integrin alpha-6 heavy chain, Integrin alpha-6 light chain, Processed integrin alpha-6, Alpha6p, ITGA6|
|Target/Specificity||Mouse anti-Human CD49f antibody, clone 450-30A recognizes the human VLA-6 cell surface antigen, also known as the alpha 6 integrin and as CD49f.CD49f is expressed by platelets, weakly by monocytes and by a subset of lymphocytes. CD49f is also widely expressed on epithelial tissues.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD49f Antibody, clone 450-30A is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Kennel, S.J. et al. (1990) Second generation monoclonal antibodies to the human integrin alpha 6 beta 4.Hybridoma. 9 (3): 243-55. 2. Maurice, S. et al. (2007) Isolation of progenitor cells from cord blood using adhesion matrices.Cytotechnology. 54: 121-33. 3. Cavers, M. et al. (2002) Differential expression of beta1 and beta2 integrins and L-selectin on CD4+ and CD8+ T lymphocytes in human blood: comparative analysis between isolated cells, whole blood samples and cryopreserved preparations.Clin Exp Immunol. 127: 60-5. 4. López, J. et al. (2012) Cancer-initiating cells derived from established cervical cell lines exhibit stem-cell markers and increased radioresistance.BMC Cancer. 12: 48. 5. Keller, P.J. et al. (2012) Defining the cellular precursors to human breast cancer.Proc Natl Acad Sci U S A. 109: 2772-7. 6. Kaczmarek, M. et al. (2011) Evaluation of the phenotype pattern of macrophages isolated from malignant and non-malignant pleural effusions.Tumour Biol. 32: 1123-32. 7. Aldridge, V. et al. (2012) Human mesenchymal stem cells are recruited to injured liver in a ß1-integrin and CD44 dependent manner.Hepatology. 56 (3): 1063-73. 8. Steinberg, F. et al. (2012) SNX17 protects integrins from degradation by sorting between lysosomal and recycling pathways.J Cell Biol. 197 (2): 219-30. 9. Liu, L. et al. (2003) Priming of eosinophil migration across lung epithelial cell monolayers and upregulation of CD11b/CD18 are elicited by extracellular Ca2+.Am J Respir Cell Mol Biol. 28: 713-21.
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