|Calculated MW||1928 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Shelf Life||18 months from date of despatch.|
|Other Names||T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4, CD4|
|Target/Specificity||Mouse anti-Sheep CD4 antibody, clone 44.38 recognizes the ovine CD4 cell surface glycoprotein, which is expressed by a subset of mature T lymphocytes. Mouse anti-Sheep CD4 antibody, clone 44.38 immunoprecipitates a protein of ~56 kDa under reducing conditions.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or -20℃.|
|Precautions||Anti-Sheep CD4 Antibody, clone 44.38 (FITC) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Maddox, J. et al. (1985) Surface antigens, SBU-T4 and SBU-T8, of sheep T lymphocyte subsets defined by monoclonal antibodies. Immunology. 55: 739 - 748. 2. Mackay, C. et al. (1986) Three distinct subpopulations of sheep T lymphocytes. Eur. J. Immunol. 16: 19 - 25. 3. Mackay, C. et al. (1987) A monoclonal antibody to the p220 component of sheep LCA identifies B cells and a unique lymphocyte subset . Cell. Immunol. 110: 46 - 55. 4. Mackay, C. et al. (1986) Thymocyte subpopulations during early fetal development in sheep. J. Immunol. 136 (5): 1592 - 1599. 5. Breugelmans, S. et al. (2010) Immunoassay of lymphocyte subsets in ovine palatine tonsils.Acta Histochem. 113: 416-22. 6. Connelley, T. et al. (2011) NKp46 defines ovine cells that have characteristics corresponding to NK cells.Vet Res. 42: 37. 7. Brown, M.N. et al. (2010) Chemoattractant receptors and lymphocyte egress from extralymphoid tissue: changing requirements during the course of inflammation.J Immunol. 185: 4873-82. 8. Chan, S.S. et al. (2002) Generation and characterization of ovine dendritic cells derived from peripheral blood monocytes.Immunology. 107: 366-72. 9. Foulon, E. et al. (2008) Two populations of ovine bone marrow-derived dendritic cells can be generated with recombinant GM-CSF and separated on CD11b expression.J Immunol Methods. 339: 1-10. 10. Debes, G.F. et al. (2005) Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues.Nat Immunol. 6: 889-94. 11. Gillan, S. et al. (2010) Identification of immune parameters to differentiate disease states among sheep infected with Mycobacterium avium subsp. paratuberculosis.Clin Vaccine Immunol. 17: 108-17. 12. Lacroux, C. et al. (2011) Prionemia and leuco-platelet associated infectivity in sheep TSE models.J Virol. 86: 2056-66. 13. Summers, C. et al. (2012) The distribution of immune cells in the lungs of classical and atypical ovine pulmonary adenocarcinoma.Vet Immunol Immunopathol. 146: 1-7. 14. Lybeck, K.R. et al. (2012) Intestinal Strictures, Fibrous Adhesions and High Local Interleukin-10 Levels in Goats Infected Naturally with Mycobacterium aviumsubsp.paratuberculosis.J Comp Pathol. 148: 157-72. 15. Umeshappa, C.S. et al. (2010) Cell-mediated immune response and cross-protective efficacy of binary ethylenimine-inactivated bluetongue virus serotype-1 vaccine in sheep.Vaccine. 28: 2522-31. 16. Kalyanasundaram, A. et al. (2015) Comparative immunoprophylactic efficacy of Haemonchus contortus recombinant enolase (rHcENO) and Con A purified native glycoproteins in sheep.Exp Parasitol. 154: 98-107.1. Lybeck, K. R. et al. (2009) Neutralization of interleukin-10 from CD14(+) monocytes enhances gamma interferon production in peripheral blood mononuclear cells from Mycobacterium avium subsp. paratuberculosis-infected goats. Clin. Vaccine. Immunol. 16: 1003-11.
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