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>   home   >   Products   >   Primary Antibodies   >   Anti-Sheep MHC Class II DR Monomorphic Antibody, clone 37.68 (FITC)   

Anti-Sheep MHC Class II DR Monomorphic Antibody, clone 37.68

Mouse Anti-Sheep Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Reactivity Sheep
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names 37.68
Additional Information
Other Species Ga,H,B
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Splenocytes from ATL mice.
Shelf Life 18 months from date of despatch.
Target/Specificity Mouse anti-Sheep MHC class II antibody, clone 37.68 recognises a monomorphic epitope on ovine MHC class II DR molecules, constitutively expressed on antigen presenting cells such as dendritic cells, B lymphocytes, monocytes, macrophages, activated T lymphocytes and may be induced on a range of other cell types by interferon gamma.The major histocompatibility complex (MHC) is a cluster of genes some of which are important in the immune response to infections. In sheep, this complex is referred to as the ovine leukocyte antigen (OLA) region. There are 2 major types of MHC class IIa molecules encoded by the OLA which are DR and DQ each composed of an alpha and beta chain.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Sheep MHC Class II DR Monomorphic Antibody, clone 37.68 is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Puri, N. et al. (1985) Sheep lymphocyte antigens (OLA) II. Major histocompatibility complex class II molecules.
Immunology. 56: 725 - 733. 2. Puri, N. et al. (1987) Monoclonal antibodies to sheep MHC class I and class II molecules: biochemical characterization of three class I gene products and four distinct subpopulations of class II molecules.
Vet. Immunol. Immunopathol. 15: 59 - 86. 3. Puri, N. et al. (1987) Sheep MHC class II molecules. II. Identification and characterization of four distinct subsets of sheep MHC class II molecule.
Immunology. 62: 575 - 580. 4. Puri, N. et al. (1987) Monoclonal antibodies to sheep MHC class II molecules recognize all HLA-D or subsets of HLA-D region products.
Hum. Imunol. 20: 195 - 207. 5. Ballingall. K. et al. (1995) Analysis of the fine specificities of sheep major histocompatatibility complex class II - specific monoclonal antibodies using mouse L - cell transfectants.
Anim. Genet. 26: 79-84.

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Cat# ABD12203
(40 western blots)
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