|Application ||IF, FC, IP|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Peripheral blood leukocytes from white leghorn chicken.|
|Shelf Life||12 months from date of reconstitution.|
|Target/Specificity||Mouse anti-Chicken CD41/61, clone 11C3 recognizes the chicken integrin CD41/61, also known as GPIIb-IIIa. CD41/61 is a heterodimeric cell surface protein that is expressed on chicken thrombocytes and cells of the thrombocyte lineage. Avian thrombocytes are nucleated equivalents of mammalian platelets that play a role in coagulation and phagocytosis. Mouse anti-Chicken CD41/61 clone 11C3 is reported to induce thrombocyte activation (Lacoste-Eleaumeet al.1994).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Storage at 4℃ or at -20℃.|
|Precautions||Anti-Chicken CD41/CD61 Antibody, clone 11C3 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Lacoste-Eleaume, A.S. et al. (1994) Biochemical and functional characterization of an Avian homolog of the integrin GPIIb-IIa present on chicken thrombocytes. Exp. Cell. Res. 213: 198 - 209. 2. Corbel, C. et al. (2002) Expression of alpha V beta 3 integrin in the chick embryo aortic endothelium. Int. J. Dev. 46: 827 - 830. 3. Del Cacho, E. et al. (2008) Isolation of chicken follicular dendritic cells.J Immunol Methods. 334: 59-69. 4. Del Cacho, E. et al. (2009) Avian follicular and interdigitating dendritic cells: isolation and morphologic, phenotypic, and functional analyses.Vet Immunol Immunopathol. 129: 66-75. 5. Ody, C. et al. (1999) Glycoprotein IIb-IIIa is expressed on avian multilineage hematopoietic progenitor cells.Blood. 93: 2898-906. 6. Chaussé, A.M. et al. (2011) Expression of Toll-like receptor 4 and downstream effectors in selected cecal cell subpopulations of chicks resistant or susceptible to Salmonella carrier state.Infect Immun. 79: 3445-54. 7. Balic, A. et al. (2014) Visualisation of chicken macrophages using transgenic reporter genes: insights into the development of the avian macrophage lineage.Development. 141: 3255-65.
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